(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

Base Information

Chemical Name:(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate
CAS No.:954143-60-3
Molecular Formula:C₂₂H₂₃Cl₄NO₅
Molecular Weight:523.24
Hs Code.:

Synonyms:(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

Suppliers and Price of (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

Chemical Property:

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Technology Process of (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

There total 8 articles about (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 934562-65-9
(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl alcohol

: 3744-87-4,7764-95-6,15761-38-3
Boc-(R)-Ala

: 954143-60-3
(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

Guidance literature:: With dmap; dacarbazine; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1055/s-2007-983801

Reference yield:

: 954143-68-1
C₂₂H₂₆ClNO₅

: 954143-60-3
(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

Guidance literature:: Multi-step reaction with 6 steps

1: CH₂Cl₂ / 20 °C

2: DMAP; DIC / CH₂Cl₂ / 20 °C

3: CH₂Cl₂ / 20 °C

4: DMAP; DIC / CH₂Cl₂ / 20 °C

5: CH₂Cl₂ / 20 °C

6: 92 percent / DMAP; DIC / CH₂Cl₂ / 3 h / 20 °C

With dmap; dacarbazine; In dichloromethane;
DOI:10.1055/s-2007-983801

Reference yield:

: 954143-66-9
C₂₂H₂₅Cl₂NO₅

: 954143-60-3
(2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate

Guidance literature:: Multi-step reaction with 6 steps

1: CH₂Cl₂ / 20 °C

2: DMAP; DIC / CH₂Cl₂ / 20 °C

3: CH₂Cl₂ / 20 °C

4: DMAP; DIC / CH₂Cl₂ / 20 °C

5: CH₂Cl₂ / 20 °C

6: 92 percent / DMAP; DIC / CH₂Cl₂ / 3 h / 20 °C

With dmap; dacarbazine; In dichloromethane;
DOI:10.1055/s-2007-983801