4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

Base Information

Chemical Name:4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide
CAS No.:1435952-00-3
Molecular Formula:C₁₇H₁₉N₇OS
Molecular Weight:369.45
Hs Code.:

Synonyms:4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

Suppliers and Price of 4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

There total 6 articles about 4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1435953-81-3
7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-ylamine hydrochloride

: 622-58-2,374675-64-6
p-Tolylisocyanate

: 1435952-00-3
4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

Reference yield:

: 171887-03-9
N-(2-amino-4,6-dichloropyrimidin-5-yl)formamide

: 1435952-00-3
4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

Guidance literature:: Multi-step reaction with 4 steps

1: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / 1 h / 55 °C

2: Lawessons reagent / tetrahydrofuran / 1.5 h / 70 °C

3: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

4: triethylamine / N,N-dimethyl-formamide / 4 h / 20 °C

With Lawessons reagent; hydrogenchloride; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;

Reference yield:

: 1435953-79-9
4-[2-amino-6-chloro-5-(formylamino)pyrimidin-4-yl]piperazine-1-carboxylic acid tert-butyl ester

: 1435952-00-3
4-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-piperazine-1-carboxylic acid p-tolylamide

Guidance literature:: Multi-step reaction with 3 steps

1: Lawessons reagent / tetrahydrofuran / 1.5 h / 70 °C

2: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

3: triethylamine / N,N-dimethyl-formamide / 4 h / 20 °C

With Lawessons reagent; hydrogenchloride; triethylamine; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;