(2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline

Base Information

• Chemical Name: (2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline
• CAS No.: 804549-36-8
• Molecular Formula: C₁₃H₂₁NO₄
• Molecular Weight: 257.298
• Mol file: 804549-36-8.mol

Synonyms:(2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline

Chemical Property of (2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline

There total 1 articles about (2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,4R)-N-Boc-4,2'-dideuterio-4-(Z)-propenylprolinol → (2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline (804549-36-8)

Guidance literature:

With jones reagent; In acetone; at 4 ℃; for 2h;

DOI:10.1002/chem.200400406

Reference yield: 93.0%

(2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline (804549-36-8) + 1-bromomethyl-4-nitro-benzene (100-11-8) → p-nitrobenzyl (2S,4R)-N-Boc-4,2'-dideuterio-4-(Z)-propenylprolinate (804549-21-1)

Guidance literature:

With potassium carbonate; In acetonitrile; at 70 ℃; for 3h;

DOI:10.1002/chem.200400406

Reference yield: 36.0%

(2S,4R)-N-Boc-4,2'-Dideuterio-4-(Z)-propenylproline (804549-36-8) → (2S,4R)-4,2'-dideuterio-4-(Z)-propenylproline

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 0.333333h;

DOI:10.1002/chem.200400406

Downstream raw materials:

p-nitrobenzyl (2S,4R)-N-Boc-4,2'-dideuterio-4-(Z)-propenylprolinate