C₂₃H₃₀O₃Si

Base Information

• Chemical Name: C₂₃H₃₀O₃Si
• CAS No.: 1477482-20-4
• Molecular Formula: C₂₃H₃₀O₃Si
• Molecular Weight: 382.575
• Mol file: 1477482-20-4.mol

Synonyms:C₂₃H₃₀O₃Si

Chemical Property of C₂₃H₃₀O₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₀O₃Si

There total 5 articles about C₂₃H₃₀O₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

chloromethyl methyl ether (107-30-2) + 5-(tert-butyl-diphenyl-silanyloxy)-pent-1-yn-3-ol (225114-91-0) → C23H30O3Si (1477482-20-4)

Guidance literature:

5-(tert-butyl-diphenyl-silanyloxy)-pent-1-yn-3-ol; With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 0.166667h;

chloromethyl methyl ether; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1055/s-0033-1339493

Reference yield:

3-(tert-butyldiphenylsilyloxy)-1-propanal (112897-03-7) → C23H30O3Si (1477482-20-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: (R)-1,1'-Bi-2-naphthol; diethylzinc; titanium(IV) isopropylate / dichloromethane; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / 2 h / 20 °C

1.2: 12 h / 20 °C

2.1: potassium carbonate / methanol / 1 h / 0 - 20 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.17 h / 0 °C

3.2: 4 h / 20 °C

With titanium(IV) isopropylate; diethylzinc; (R)-1,1'-Bi-2-naphthol; tetra-(n-butyl)ammonium iodide; potassium carbonate; N-ethyl-N,N-diisopropylamine; In methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; dichloromethane;

DOI:10.1055/s-0033-1339493

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → C23H30O3Si (1477482-20-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydride / nujol; tetrahydrofuran / 12 h / 0 - 20 °C / Inert atmosphere

1.2: 1 h / 0 °C

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.25 h / -78 °C / Inert atmosphere

2.2: -78 °C / Inert atmosphere

3.1: (R)-1,1'-Bi-2-naphthol; diethylzinc; titanium(IV) isopropylate / dichloromethane; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / 2 h / 20 °C

3.2: 12 h / 20 °C

4.1: potassium carbonate / methanol / 1 h / 0 - 20 °C / Inert atmosphere

4.2: Inert atmosphere

5.1: tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.17 h / 0 °C

5.2: 4 h / 20 °C

With titanium(IV) isopropylate; oxalyl dichloride; diethylzinc; (R)-1,1'-Bi-2-naphthol; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; nujol; hexane; dichloromethane; 2.2: |Swern Oxidation;

DOI:10.1055/s-0033-1339493

upstream raw materials:

3-(tert-butyldiphenylsilyloxy)propan-1-ol

tert-butylchlorodiphenylsilane

3-(tert-butyldiphenylsilyloxy)-1-propanal

(S)-5-((tert-butyldiphenylsilyl)oxy)-1-(trimethylsilyl)pent-1-yn-3-ol

Downstream raw materials:

C₄₃H₅₂O₆SSi

C₂₃H₂₉BrO₃SiZn