(R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

Base Information

Chemical Name:(R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine
CAS No.:1191280-70-2
Molecular Formula:C₃₆H₄₃NO₂
Molecular Weight:523.727
Hs Code.:

Synonyms:(R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

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Chemical Property of (R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

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Technology Process of (R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

There total 8 articles about (R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1191280-69-9
(R)-3-(2-(benzyloxy)-5-(benzyloxy(methyl-d2))phenyl)-N,N-diisopropyl-3-phenylpropanamide

: 1191280-70-2
(R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

Guidance literature:: (R)-3-(2-(benzyloxy)-5-(benzyloxy(methyl-d2))phenyl)-N,N-diisopropyl-3-phenylpropanamide; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 14h;

With sodium hydroxide; In tetrahydrofuran; water;

Reference yield:

: 1191280-67-7
(R)-3-(2-(benzyloxy)-5-(benzyloxy(methyl-d2))phenyl)-3-phenylpropanoic acid

: 1191280-70-2
(R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; thionyl chloride / toluene / 1 h / Reflux

2: triethylamine / diethyl ether / 4 h

3: lithium aluminium tetrahydride / tetrahydrofuran / 14 h / 20 °C

With pyridine; lithium aluminium tetrahydride; thionyl chloride; triethylamine; In tetrahydrofuran; diethyl ether; toluene;

Reference yield:

: 1191280-68-8
(R)-3-(2-(benzyloxy)-5-(benzyloxy(methyl-d2))phenyl)-3-phenylpropanoyl chloride

: 1191280-70-2
(R)-3-(2-(benzyloxy)-5-(benzyloxymethyl-d2)phenyl)-N,N-diisopropyl-3-phenylpropan-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / diethyl ether / 4 h

2: lithium aluminium tetrahydride / tetrahydrofuran / 14 h / 20 °C

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; diethyl ether;