(S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride

Base Information

Chemical Name:(S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride
CAS No.:1613413-98-1
Molecular Formula:C₂₂H₂₁NO₃*ClH
Molecular Weight:383.875
Hs Code.:

Synonyms:(S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride

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Chemical Property of (S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride

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Technology Process of (S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride

There total 10 articles about (S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1613413-97-0
(S)-methyl 4-((3-((((tert-butoxy)carbonyl)amino)(phenyl)methyl)phenoxy)methyl)benzoate

: 1613413-98-1
(S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 16h;

Reference yield:

: 1416069-62-9
(S)-tert-butyl ((3-hydroxyphenyl)(phenyl)methyl)carbamate

: 1613413-98-1
(S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: CHIRALPAK AD 20 / isopropyl alcohol; n-heptane; diethylamine / 25 °C / Resolution of racemate

2: potassium carbonate / acetonitrile / 16 h / 20 °C

3: hydrogenchloride / methanol; 1,4-dioxane / 16 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; methanol; n-heptane; diethylamine; isopropyl alcohol; acetonitrile;

Reference yield:

: 1416070-91-1
(S)-tert-butyl ((3-hydroxyphenyl)(phenyl)methyl)carbamate

: 1613413-98-1
(S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 16 h / 20 °C

2: hydrogenchloride / methanol; 1,4-dioxane / 16 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; methanol; acetonitrile;