tetraethyldiamidophosphite

Base Information

• Chemical Name: tetraethyldiamidophosphite
• CAS No.: 3560-15-4
• Molecular Formula: C₈H₂₁N₂OP
• Molecular Weight: 192.241
• Mol file: 3560-15-4.mol

Synonyms:tetraethyldiamidophosphite

Chemical Property of tetraethyldiamidophosphite

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tetraethyldiamidophosphite

There total 6 articles about tetraethyldiamidophosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

tert-butyl(tetraethyldiamido)phosphite → tetraethyldiamidophosphite (3560-15-4) + isobutene (115-11-7,15220-85-6)

Guidance literature:

With chloroform; for 3h; Heating;

Reference yield:

o-anisylphosphonic acid bis(N,N-diethylamide) (1449303-04-1) → tetraethyldiamidophosphite (3560-15-4) + 2-methoxycyclohexa-1,4-dien-3-ylphosphonic acid bis(N,N-diethylamide) (1449303-26-7)

Guidance literature:

With ammonia; sodium; In tetrahydrofuran; at -78 ℃; for 0.0833333h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.201300344

Reference yield:

2-methoxyphenyl-bis(N,N-diethylamino)phosphane (110538-85-7) → tetraethyldiamidophosphite (3560-15-4) + 2-methoxycyclohexa-1,4-dien-3-ylphosphonic acid bis(N,N-diethylamide) (1449303-26-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dihydrogen peroxide / diethyl ether; tetrahydrofuran / 20 °C / Inert atmosphere; Schlenk technique

2: ammonia; sodium / tetrahydrofuran / 0.08 h / -78 °C / Inert atmosphere; Schlenk technique

With ammonia; dihydrogen peroxide; sodium; In tetrahydrofuran; diethyl ether; 2: |Birch Reduction;

DOI:10.1002/ejoc.201300344

upstream raw materials:

tetraethyldiamidophosphorous acid tert-butyl ester

benzaldehyde

2-methoxyphenyl-bis(N,N-diethylamino)phosphane

o-anisylphosphonic acid bis(N,N-diethylamide)

Downstream raw materials:

N,N,N',N'-Tetraaethyl-p-hydroxydiphenylmethylphosphonyl-diamid

tetraethyldiamidochlorophosphate

N,N,N',N'-Tetraaethyl-P-1-hydroxycyclohexylposphonyl-diamid

C₂₁H₃₂N₃OP