N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

Base Information

Chemical Name:N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide
CAS No.:244641-42-7
Molecular Formula:C₃₄H₃₉N₃O₅S
Molecular Weight:601.767
Hs Code.:

Synonyms:N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

Suppliers and Price of N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

Chemical Property:

Purity/Quality:: 98% HPLC ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

There total 5 articles about N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 169331-42-4
βS--αR-<<(2-methylpropyl)amino>methyl>-benzenepropanol

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 244641-42-7
N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

Guidance literature:: With triethylamine; In dichloromethane; at 23 ℃; for 2h;
DOI:10.1002/(SICI)1521-3773(19990712)38:13/14<1931::AID-ANIE1931>3.0.CO;2-4

Reference yield:

: 123054-12-6,123808-74-2,136370-73-5,111060-64-1
(2S)-N,N-dibenzylphenylalaninal

: 244641-42-7
N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / KF; O⁽⁹⁾-benzyl-N-(9-anthracenylmethyl)cinchonidium fluoride / tetrahydrofuran / 6 h / -10 °C

2: 85 percent / NaBH₄; NiCl₂ / methanol / 0.17 h / 0 °C

3: MgSO₄

4: NaBH₄ / ethanol / 4 h / 0 - 23 °C

5: 94 percent / Et₃N / CH₂Cl₂ / 2 h / 23 °C

With potassium fluoride; sodium tetrahydroborate; O⁽⁹⁾-benzyl-N-(9-anthracenylmethyl)cinchonidinium fluoride; magnesium sulfate; triethylamine; nickel dichloride; In tetrahydrofuran; methanol; ethanol; dichloromethane; 1: Addition / 2: Reduction / 3: Condensation / 4: Reduction / 5: Substitution;
DOI:10.1002/(SICI)1521-3773(19990712)38:13/14<1931::AID-ANIE1931>3.0.CO;2-4

Reference yield:

: 244641-41-6
(2R,3S)-3-(dibenzylamino)-1-nitro-4-phenylbutan-2-ol

: 244641-42-7
N-(3-dibenzylamino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / NaBH₄; NiCl₂ / methanol / 0.17 h / 0 °C

2: MgSO₄

3: NaBH₄ / ethanol / 4 h / 0 - 23 °C

4: 94 percent / Et₃N / CH₂Cl₂ / 2 h / 23 °C

With sodium tetrahydroborate; magnesium sulfate; triethylamine; nickel dichloride; In methanol; ethanol; dichloromethane; 1: Reduction / 2: Condensation / 3: Reduction / 4: Substitution;
DOI:10.1002/(SICI)1521-3773(19990712)38:13/14<1931::AID-ANIE1931>3.0.CO;2-4