Technology Process of C21H32O3S2Si
There total 5 articles about C21H32O3S2Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(R)-4-(dimethyl(phenyl)silyl)dihydrofuran-2(3H)-one;
With
n-butyllithium; diisopropylamine;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
Inert atmosphere;
(methyl-3' butanal-1'-yl-3')-2 dithianne-1,3;
With
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone;
In
tetrahydrofuran;
at -78 ℃;
for 24h;
Inert atmosphere;
DOI:10.1021/ol102278c
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: Trimethyl orthoacetate; chloro-trimethyl-silane; pyridinium p-toluenesulfonate / dichloromethane / 4 h / Inert atmosphere
1.2: Inert atmosphere
2.1: copper(l) iodide / diethyl ether / 0.33 h / -45 °C / Inert atmosphere
2.2: 3 h / Inert atmosphere
3.1: potassium osmate(VI) dihydrate / N,N-dimethyl-formamide / 0.33 h / Inert atmosphere
3.2: 3 h / 20 °C / Inert atmosphere
3.3: 1 h / 0 °C / Inert atmosphere
4.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
4.2: 24 h / -78 °C / Inert atmosphere
With
Trimethyl orthoacetate; potassium osmate(VI) dihydrate; copper(l) iodide; n-butyllithium; chloro-trimethyl-silane; pyridinium p-toluenesulfonate; diisopropylamine;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol102278c
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium osmate(VI) dihydrate / N,N-dimethyl-formamide / 0.33 h / Inert atmosphere
1.2: 3 h / 20 °C / Inert atmosphere
1.3: 1 h / 0 °C / Inert atmosphere
2.1: n-butyllithium; diisopropylamine / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
2.2: 24 h / -78 °C / Inert atmosphere
With
potassium osmate(VI) dihydrate; n-butyllithium; diisopropylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ol102278c
