methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate

Base Information

Chemical Name:methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate
CAS No.:853181-86-9
Molecular Formula:C₂₇H₂₉FN₂O₃
Molecular Weight:448.537
Hs Code.:

Synonyms:methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate

Suppliers and Price of methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate

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Technology Process of methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate

There total 1 articles about methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 140640-90-0
methyl 6-amino-4-(4-fluorophenyl)-5-formyl-2-isopropyl-nicotinate

: 54314-85-1
(3-benzyloxypropyl)triphenylphosphonium bromide

: 853181-86-9
methyl (E)-6-amino-5-(4-(phenylmethoxy)but-1-enyl)-4-(4-fluorophenyl)-2-(1-methylethyl)nicotinate

Guidance literature:: (3-benzyloxypropyl)triphenylphosphonium bromide; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; for 1h;

methyl 6-amino-4-(4-fluorophenyl)-5-formyl-2-isopropyl-nicotinate; In tetrahydrofuran; at -78 - 20 ℃; for 3.25h;