(3-Benzyloxypropyl)triphenylphosphonium bromide

Base Information

Chemical Name:(3-Benzyloxypropyl)triphenylphosphonium bromide
CAS No.:54314-85-1
Molecular Formula:C28H28 O P . Br
Molecular Weight:491.407
Hs Code.:2931900090
European Community (EC) Number:628-720-6
DSSTox Substance ID:DTXSID90448639
Mol file:54314-85-1.mol

Synonyms:54314-85-1;(3-Benzyloxypropyl)triphenylphosphonium bromide;[3-(Benzyloxy)propyl]triphenylphosphonium Bromide;triphenyl(3-phenylmethoxypropyl)phosphanium;bromide;MFCD00191781;Phosphonium, triphenyl[3-(phenylmethoxy)propyl]-, bromide;3-Benzyloxypropyl(triphenyl)phosphonium bromide;(3-(benzyloxy)propyl)triphenylphosphonium bromide;(3-Benzyloxypropyl)triphenylphosphoniumbromide;[3-(Benzyloxy)propyl]triphenylphosphoniumBromide;SCHEMBL79890;DTXSID90448639;DWYCJWXMZGVGJV-UHFFFAOYSA-M;AKOS015913243;AB87253;PS-19293;SY024113;3-Benzyloxypropyltriphenylphosphonium Bromide;CS-0183227;FT-0640237;3-benzyloxypropyl(triphenyl)phosphonium;(3-benzyloxypropyl)triphenyl phosphonium bromide;(3-benzyloxypropyl)triphenyl-phosphonium bromide;[3-(Benzyloxy)propyl](triphenyl)phosphanium bromide;triphenyl{3-[(phenylmethyl)oxy]propyl}phosphonium bromide

Suppliers and Price of (3-Benzyloxypropyl)triphenylphosphonium bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3-Benzyloxypropyl)triphenylphosphonium bromide
1g
$ 160.00

TRC
(3-Benzyloxypropyl)triphenylphosphonium bromide
10g
$ 1260.00

Sigma-Aldrich
(3-Benzyloxypropyl)triphenylphosphonium bromide 98%
5g
$ 164.00

Crysdot
(3-Benzyloxypropyl)triphenylphosphonium bromide 95+%
25g
$ 428.00

American Custom Chemicals Corporation
(3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE 95.00%
5G
$ 933.21

Alichem
(3-Benzyloxypropyl)triphenylphosphonium bromide
5g
$ 387.84

Alichem
(3-Benzyloxypropyl)triphenylphosphonium bromide
25g
$ 432.28

Alfa Aesar
(3-Benzyloxypropyl)triphenylphosphonium bromide, 97+%
25g
$ 504.00

Alfa Aesar
(3-Benzyloxypropyl)triphenylphosphonium bromide, 97+%
5g
$ 130.00

Alfa Aesar
(3-Benzyloxypropyl)triphenylphosphonium bromide, 97+%
1g
$ 35.30

Total 29 raw suppliers

Chemical Property of (3-Benzyloxypropyl)triphenylphosphonium bromide

Chemical Property:

Melting Point:153-154 °C(lit.)
PSA：22.82000
LogP:2.59140
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:9
Exact Mass:490.10612
Heavy Atom Count:31
Complexity:408

Purity/Quality:

97% ^*data from raw suppliers

(3-Benzyloxypropyl)triphenylphosphonium bromide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
Uses Reactant for preparation of:Spirocyclohexadienones via Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylationInhibitors of heat shock protein (Hsp90) as antitumor agentsCarpanone-like molecules via an oxidative coupling/Diels-Alder cycloaddition sequence (3-Benzyloxypropyl)triphenylphosphonium Bromide is a reagent used in the preparation of antitumor and Her2 degradation activity of geldanamycin and radicicol macrocyclic chimeras.

Technology Process of (3-Benzyloxypropyl)triphenylphosphonium bromide

There total 3 articles about (3-Benzyloxypropyl)triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 54314-84-0
1-[(3-bromopropoxy)methyl]-benzene

: 603-35-0
triphenylphosphine

: 54314-85-1
(3-benzyloxypropyl)triphenylphosphonium bromide

Guidance literature:: In toluene; for 7h; Heating;
DOI:10.1021/ja00295a027

Reference yield:

: 4799-68-2
3-benzyloxypropan-1-ol

: 54314-85-1
(3-benzyloxypropyl)triphenylphosphonium bromide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) methanesulfonyl chloride, triethylamine; 2.) lithium bromide / 1.) 30 min, 0 degC, CH₂Cl₂; 2.) acetone, 6 h, reflux

2: 85 percent / toluene / 7 h / Heating

With methanesulfonyl chloride; triethylamine; lithium bromide; In toluene;
DOI:10.1021/ja00295a027