2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

Base Information

Chemical Name:2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate
CAS No.:855299-71-7
Molecular Formula:C₃₉H₃₂N₄O₅
Molecular Weight:636.707
Hs Code.:

Synonyms:2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

Suppliers and Price of 2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

There total 5 articles about 2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 855299-80-8
2-[4-(N-benzylamino)-2-aminonaphthalen-1-yl]ethyl acetate

: 110314-42-6
5-(benzofuran-2-ylcarbonyl)amino-1H-indole-2-carboxylic acid

: 855299-71-7
2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In pyridine; at 20 - 60 ℃;
DOI:10.1021/jm050179u

Reference yield:

: 855299-62-6
2-[4-(N-benzylamino)-2-nitronaphthalen-1-yl]ethanol

: 855299-71-7
2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 55 percent / pyridine / 20 °C

2: H₂ / PtO₂ / tetrahydrofuran / 2 h / 20 °C / 2844.31 Torr

3: 100 percent / 1-hydroxybenzotriazole; 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide HCl / pyridine / 20 - 60 °C

With pyridine; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; platinum(IV) oxide; In tetrahydrofuran; pyridine;
DOI:10.1021/jm050179u

Reference yield:

: ethyl [4-(N-benzylamino)-2-nitronaphthalen-1-yl]acetate

: 855299-71-7
2-[4-(N-benzylamino)-2-(5-(5-benzofuran-2-carboxamido)indole-2-carboxamido)naphthalen-1-yl]ethyl acetate

Guidance literature:: Multi-step reaction with 5 steps

1: 89 percent / aq. NaOH / ethanol / 2 h / Heating

2: 55 percent / BH₃ / tetrahydrofuran

3: 55 percent / pyridine / 20 °C

4: H₂ / PtO₂ / tetrahydrofuran / 2 h / 20 °C / 2844.31 Torr

5: 100 percent / 1-hydroxybenzotriazole; 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide HCl / pyridine / 20 - 60 °C

With pyridine; sodium hydroxide; borane; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; platinum(IV) oxide; In tetrahydrofuran; pyridine; ethanol;
DOI:10.1021/jm050179u