(4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one

Base Information

Chemical Name:(4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one
CAS No.:946578-17-2
Molecular Formula:C₂₄H₂₉NO₅
Molecular Weight:411.498
Hs Code.:

Synonyms:(4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one

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Chemical Property of (4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one

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Technology Process of (4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one

There total 1 articles about (4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 946578-15-0
(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoic acid

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 946578-17-2
(4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one

Guidance literature:: (3S)-5-(4-methoxybenzyloxy)-3-methylpentanoic acid; With pivaloyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

(S)-4-Benzyl-2-oxazolidinone; With lithium chloride; In tetrahydrofuran; dichloromethane; at 0 - 25 ℃;
DOI:10.1246/bcsj.80.1173

Reference yield: 53.0%

: 946578-17-2
(4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one

: 74-88-4
methyl iodide

: 946578-19-4
(4S)-4-benzyl-3-[(2S,3S)-2,3-dimethyl-5-(4-methoxybenzyloxy)pentanoyl]oxazolidin-2-one

Guidance literature:: (4S)-4-benzyl-3-[(3S)-5-(4-methoxybenzyloxy)-3-methylpentanoyl]oxazolidin-2-one; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at -78 ℃; for 33h; stereoselective reaction;
DOI:10.1246/bcsj.80.1173