(RS)-benzyl β-malolactonate

Base Information

• Chemical Name: (RS)-benzyl β-malolactonate
• CAS No.: 76652-44-3
• Molecular Formula: C₁₁H₁₀O₄
• Molecular Weight: 206.198
• Mol file: 76652-44-3.mol

Synonyms:(RS)-benzyl β-malolactonate

Chemical Property of (RS)-benzyl β-malolactonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (RS)-benzyl β-malolactonate

There total 3 articles about (RS)-benzyl β-malolactonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromosuccinic acid (923-06-8,584-98-5) + benzyl bromide (100-39-0) → (RS)-benzyl β-malolactonate (76652-44-3)

Guidance literature:

bromosuccinic acid; With trifluoroacetic anhydride; In tetrahydrofuran; for 2h; cooling;

benzyl bromide; at 45 ℃; for 12h;

With sodium hydroxide; In water; pH=7.2; Further stages.;

DOI:10.1021/ma050545j

Reference yield:

RS-3-benzyloxycarbonyl-3-bromopropanoic acid (197014-62-3) + 2-bromo-succinic acid 4-benzyl ester (88850-36-6) → (RS)-benzyl β-malolactonate (76652-44-3)

Guidance literature:

With sodium hydroxide; In dichloromethane; at 45 ℃; for 3h; pH=7.2;

DOI:10.3390/molecules26247703

Reference yield:

3-bromodihydro-2,5-furandione (5470-44-0) + benzyl alcohol (100-51-6,185532-71-2) → (RS)-benzyl β-malolactonate (76652-44-3)

Guidance literature:

3-bromodihydro-2,5-furandione; benzyl alcohol; at 20 - 60 ℃; for 5h;

With sodium hydroxide; In water; benzene; at 50 ℃; pH=7.8;

DOI:10.1021/bc900422j

upstream raw materials:

bromosuccinic acid

benzyl bromide

3-bromodihydro-2,5-furandione

benzyl alcohol

Downstream raw materials:

malolactone