C₅₃H₅₄N₂O₉

Base Information

• Chemical Name: C₅₃H₅₄N₂O₉
• CAS No.: 1403576-36-2
• Molecular Formula: C₅₃H₅₄N₂O₉
• Molecular Weight: 863.02
• Mol file: 1403576-36-2.mol

Synonyms:C₅₃H₅₄N₂O₉

Chemical Property of C₅₃H₅₄N₂O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₅₃H₅₄N₂O₉

There total 7 articles about C₅₃H₅₄N₂O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,6-tetra-O-benzyl-α/β-D-glucopyranosyl bromide (67773-43-7) + ethyl 1-(2-hydroxyethyl)-2-(4-methoxyphenyl)-1H-benzimidazole-5-carboxylate (1379150-05-6) → C53H54N2O9 (1403576-36-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.3390/molecules17089887

Reference yield:

3-nitro-4-fluorobenzoic acid (453-71-4) → C53H54N2O9 (1403576-36-2)

Guidance literature:

Multi-step reaction with 5 steps

1: sulfuric acid / 8 h / Reflux

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

3: 10% Pd/C; ammonium formate / ethanol / 0.03 h / 100 °C / Microwave irradiation

4: N,N-dimethyl-formamide / 0.03 h / 130 °C / Microwave irradiation

5: N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 20 °C / Inert atmosphere

With sulfuric acid; 10% Pd/C; ammonium formate; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.3390/molecules17089887

Reference yield:

2,3,4,6-Tetra-O-benzyl-D-glucopyranose (4291-69-4,6386-24-9,6564-72-3,59531-24-7,69257-52-9,78184-89-1,78609-16-2,78609-17-3,78609-18-4,96553-53-6,104111-61-7,131347-08-5,4132-28-9) → C53H54N2O9 (1403576-36-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine; carbon tetrabromide / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 20 °C / Inert atmosphere

With carbon tetrabromide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In dichloromethane;

DOI:10.3390/molecules17089887

upstream raw materials:

3-nitro-4-fluorobenzoic acid

sodium hydroxy(4-methoxyphenyl)methanesulfonate

2,3,4,6-tetra-O-benzyl-α/β-D-glucopyranosyl bromide

ethyl 1-(2-hydroxyethyl)-2-(4-methoxyphenyl)-1H-benzimidazole-5-carboxylate

Downstream raw materials:

C₂₅H₃₀N₂O₉