(4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

Base Information

Chemical Name:(4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane
CAS No.:220691-27-0
Molecular Formula:C₁₈H₂₈O₃
Molecular Weight:292.419
Hs Code.:

Synonyms:(4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

Suppliers and Price of (4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

There total 2 articles about (4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 116-11-0
2-Methoxypropene

: 220691-93-0
(3R,4S,5S)-6-Benzyloxy-3,5-dimethyl-hexane-1,4-diol

: 220691-27-0
(4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

Guidance literature:: With pyridinium p-toluenesulfonate; In dichloromethane;

Reference yield:

: 106357-31-7
(2S,3S,4R)-1-benzyloxy-2,4-dimethylhex-5-ene-3-ol

: 220691-27-0
(4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 9-BBN, 2.) NaOH, H₂O₂ / 1.) THF, 65 deg C, 2.) THF, H₂O, 0 deg C to r.t.

2: 96 percent / PPTS / CH₂Cl₂

With sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; dihydrogen peroxide; pyridinium p-toluenesulfonate; In dichloromethane;

Reference yield:

: 220691-27-0
(4S,5R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxepane

: 220691-98-5
C₅₂H₈₂O₈Si₂

Guidance literature:: Multi-step reaction with 17 steps

1: Na, NH₃ / diethyl ether

2: PPTS / CH₂Cl₂

3: Et₃N / CH₂Cl₂ / -5 °C

4: NaI, molecular sieves 4 Angstroem / butan-2-one / 45 °C

5: 1.) BuLi, DMPU / 1.) THF, -78 deg C, 2.) THF

6: CSA / methanol

7: TPAP, NMO, molecular sieves 4 Angstroem / CH₂Cl₂

8: Ph₃P / 0 °C

9: BuLi

10: 1.) BuLi, Me₂AlCl / 1.) PhMe, 0 deg C; CH₂Cl₂, 0 deg C to r.t., 2.) PhMe, CH₂Cl₂

11: 1.) 9-BBN, 2.) NaOH, H₂O₂ / 1.) THF, reflux, 2.) THF, H₂O₂, r.t.

12: NaBH₄ / ethanol / 0 °C

13: 95 percent / 2,6-lutidine / CH₂Cl₂

14: 95 percent / H₂ / Pd/C / methanol; CH₂Cl₂

15: 97 percent / TPAP, NMO, molecular sieves 4 Angstroem / CH₂Cl₂

16: 90 percent / toluene / Heating

17: 98 percent / CAN, H₂O / acetonitrile; tetrahydrofuran / 0 °C

With 2,6-dimethylpyridine; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; sodium hydroxide; sodium tetrahydroborate; 9-borabicyclo[3.3.1]nonane dimer; n-butyllithium; N-methyl-2-indolinone; tetrapropylammonium perruthennate; ammonium cerium(IV) nitrate; 4 A molecular sieve; camphor-10-sulfonic acid; ammonia; water; hydrogen; dihydrogen peroxide; sodium; dimethylaluminum chloride; pyridinium p-toluenesulfonate; triethylamine; triphenylphosphine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; toluene; acetonitrile; butanone;