3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate

Base Information

Chemical Name:3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate
CAS No.:1145786-72-6
Molecular Formula:C₂HF₃O₂*C₁₆H₁₅ClN₄O
Molecular Weight:428.798
Hs Code.:

Synonyms:3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate

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Chemical Property of 3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate

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Technology Process of 3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate

There total 1 articles about 3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.4%

: 19064-64-3
3,6-dichloro-4-methylpyridazine

: 1145786-45-3
[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]boronic acid

: 76-05-1
trifluoroacetic acid

: 1145786-72-6
3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate

Guidance literature:: 3,6-dichloro-4-methylpyridazine; [4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]boronic acid; With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,2-dimethoxyethane; water; for 3h; Heating / reflux;

trifluoroacetic acid;

Reference yield: 66.0%

: 1145786-72-6
3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate

: 4152-90-3
m-chlorobenzylamine

: 1145786-37-3
N-[(3-chlorophenyl)methyl]-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-3-pyridazinamine

Guidance literature:: With caesium carbonate; triethylamine; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; for 3h; Heating / reflux;

Reference yield: 48.0%

: 89-93-0
ortho-methylbenzylamine

: 1145786-72-6
3-chloro-4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]pyridazine trifluoroacetate

: 1145786-39-5
4-methyl-6-[4-(4-methyl-1H-imidazol-1-yl)-3-(methyloxy)phenyl]-N-[(2-methylphenyl)methyl]-3-pyridazinamine

Guidance literature:: With caesium carbonate; triethylamine; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; for 3h; Heating / reflux;