7-(4-Methoxy-benzyl)-3-methyl-5H-isoxazolo[4,5-d]pyridazin-4-one

Base Information

Chemical Name:7-(4-Methoxy-benzyl)-3-methyl-5H-isoxazolo[4,5-d]pyridazin-4-one
CAS No.:129663-30-5
Molecular Formula:C₁₄H₁₃N₃O₃
Molecular Weight:271.276
Hs Code.:
DSSTox Substance ID:DTXSID801151296
Nikkaji Number:J339.829C

Synonyms:DTXSID801151296;129663-30-5;7-(4-Methoxy-benzyl)-3-methyl-5H-isoxazolo[4,5-d]pyridazin-4-one;7-[(4-Methoxyphenyl)methyl]-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one

Suppliers and Price of 7-(4-Methoxy-benzyl)-3-methyl-5H-isoxazolo[4,5-d]pyridazin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-(4-Methoxy-benzyl)-3-methyl-5H-isoxazolo[4,5-d]pyridazin-4-one

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:271.09569129
Heavy Atom Count:20
Complexity:405

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NOC2=C1C(=O)NN=C2CC3=CC=C(C=C3)OC

Technology Process of 7-(4-Methoxy-benzyl)-3-methyl-5H-isoxazolo[4,5-d]pyridazin-4-one

There total 5 articles about 7-(4-Methoxy-benzyl)-3-methyl-5H-isoxazolo[4,5-d]pyridazin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 129663-17-8
5-[(Z)-1-Hydroxy-2-(4-methoxy-phenyl)-vinyl]-3-methyl-isoxazole-4-carboxylic acid ethyl ester

: 129663-30-5
7-(4-methoxybenzyl)-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one

Guidance literature:: With hydrazine hydrate; In ethanol; for 2h; Heating;

Reference yield: 70.0%

: 1309666-13-4
methyl 5-(1-hydroxy-2-(4-methoxyphenyl)vinyl)-3-methylisoxazole-4-carboxylate

: 129663-30-5
7-(4-methoxybenzyl)-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one

Guidance literature:: With hydrazine hydrate; In ethanol; for 2h; Reflux;
DOI:10.3906/kim-1004-584

Reference yield:

: 60404-04-8
5-(4-methoxy-benzylidene)-2-methyl-4-oxo-4,5-dihydro-furan-3-carboxylic acid ethyl ester

: 129663-30-5
7-(4-methoxybenzyl)-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / sodium acetate, hydroxylamine hydrochloride / ethanol; H₂O / 2 h / Heating

2: 74 percent / hydrazine hydrate / ethanol / 2 h / Heating

With hydroxylamine hydrochloride; sodium acetate; hydrazine hydrate; In ethanol; water;