1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

Base Information

Chemical Name:1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide
CAS No.:1374202-06-8
Molecular Formula:C₁₈H₂₀N₆O₄S
Molecular Weight:416.461
Hs Code.:

Synonyms:1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

Suppliers and Price of 1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

There total 3 articles about 1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1374202-31-9
2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo[4,5-d]pyridazin-5(4H)-yl)acetohydrazide

: 556-61-6
methyl thioisocyanate

: 1374202-06-8
1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

Guidance literature:: In ethanol; for 4h; Reflux;
DOI:10.1016/j.bmc.2012.03.021

Reference yield:

: 1374202-29-5
ethyl 2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo[4,5-d]pyridazin-5(4H)-yl)acetate

: 1374202-06-8
1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 1 h / Reflux

2: ethanol / 4 h / Reflux

With hydrazine hydrate; In ethanol;
DOI:10.1016/j.bmc.2012.03.021

Reference yield:

: 129663-30-5
7-(4-methoxybenzyl)-3-methylisoxazolo[4,5-d]pyridazin-4(5H)-one

: 1374202-06-8
1-(2-(7-(4-methoxybenzyl)-3-methyl-4-oxoisoxazolo-[4,5-d]pyridazin-5(4H)-yl)acetyl)-4-methylthiosemicarbazide

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / 4 h / Reflux

1.2: 2 h / Reflux

2.1: hydrazine hydrate / ethanol / 1 h / Reflux

3.1: ethanol / 4 h / Reflux

With hydrazine hydrate; potassium carbonate; In ethanol; acetone;
DOI:10.1016/j.bmc.2012.03.021