3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane)

Base Information

• Chemical Name: 3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane)
• CAS No.: 125016-58-2
• Molecular Formula: C₁₆H₁₈OS₂
• Molecular Weight: 290.45
• Mol file: 125016-58-2.mol

Synonyms:3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane)

Chemical Property of 3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane)

There total 3 articles about 3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-benzoyl-2-(1-(pentan-3-onyl))-1,3-dithiane (125016-54-8) → 3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane) (125016-58-2)

Guidance literature:

With sodium ethanolate; In ethanol; Heating;

DOI:10.1016/S0040-4020(01)89242-5

Reference yield:

benzonitrile (100-47-0) → 3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane) (125016-58-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) n-butyllithium / 1.) THF, hexane, -40 deg C, 2 h 2.) THF, -78 deg C

2: 100 percent / zinc chloride / CH₂Cl₂ / 48 h / 0 °C

3: 100 percent / sodium ethoxide / ethanol / Heating

With n-butyllithium; sodium ethanolate; zinc(II) chloride; In ethanol; dichloromethane;

DOI:10.1016/S0040-4020(01)89242-5

Reference yield:

<2-(1,3-dithianylidene)>-phenylmethylamine (115994-27-9) → 3-methyl-2-phenylcyclohex-2-en-4-one spiro-1,2'-(1',3'-dithiane) (125016-58-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / zinc chloride / CH₂Cl₂ / 48 h / 0 °C

2: 100 percent / sodium ethoxide / ethanol / Heating

With sodium ethanolate; zinc(II) chloride; In ethanol; dichloromethane;

DOI:10.1016/S0040-4020(01)89242-5

upstream raw materials:

2-benzoyl-2-(1-(pentan-3-onyl))-1,3-dithiane

benzonitrile

<2-(1,3-dithianylidene)>-phenylmethylamine