Furo[3,4-b]pyrazine-2,5,7(1H)-trione

Base Information

Chemical Name:Furo[3,4-b]pyrazine-2,5,7(1H)-trione
CAS No.:73403-50-6
Molecular Formula:C₆H₂N₂O₄
Molecular Weight:166.093
Hs Code.:
DSSTox Substance ID:DTXSID40504552
Wikidata:Q82359124
Mol file:73403-50-6.mol

Synonyms:73403-50-6;Furo[3,4-b]pyrazine-2,5,7(1H)-trione;2-Hydroxyfuro[3,4-b]pyrazine-5,7-dione;4H-furo[3,4-b]pyrazine-3,5,7-trione;DTXSID40504552

Suppliers and Price of Furo[3,4-b]pyrazine-2,5,7(1H)-trione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
Furo[3,4-b]pyrazine-2,5,7(1H)-trione 97.00%
25G
$ 13300.00

AccelPharmtech
Furo[3,4-b]pyrazine-2,5,7(1H)-trione 97.00%
5G
$ 5360.00

Total 4 raw suppliers

Chemical Property of Furo[3,4-b]pyrazine-2,5,7(1H)-trione

Chemical Property:

PSA：89.12000
LogP:-0.91950
XLogP3:-0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:166.00145655
Heavy Atom Count:12
Complexity:366

Purity/Quality:

99% ^*data from raw suppliers

Furo[3,4-b]pyrazine-2,5,7(1H)-trione 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC2=C(C(=O)OC2=O)NC1=O

Technology Process of Furo[3,4-b]pyrazine-2,5,7(1H)-trione

There total 2 articles about Furo[3,4-b]pyrazine-2,5,7(1H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73403-52-8
1,6-dihydro-6-oxo-2,3-pyrazinedicarboxamide

: 73403-50-6
1H-furo<3,4-b>pyrazine-2,5,7-trione

Guidance literature:: With sodium hydroxide; thionyl chloride; Yield given. Multistep reaction; 1.) reflux, 5 h; 2.) reflux, 3 h;
DOI:10.1248/cpb.28.3057

Reference yield:

: 57005-60-4
1,6-dihydro-6-oxo-2,3-pyrazinedicarbonitrile

: 73403-50-6
1H-furo<3,4-b>pyrazine-2,5,7-trione

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / conc. HCl / Ambient temperature

2: 1.) 10percent NaOH; 2.) SOCl₂ / 1.) reflux, 5 h; 2.) reflux, 3 h

With hydrogenchloride; sodium hydroxide; thionyl chloride;
DOI:10.1248/cpb.28.3057

Reference yield:

: 73403-50-6
1H-furo<3,4-b>pyrazine-2,5,7-trione

: 13924-98-6
methyl 1,6-dihydro-6-oxo-2-pyrazinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 5 h / Heating

2: 56 percent / nitrobenzene / 7 h / 180 - 190 °C

With nitrobenzene;
DOI:10.1248/cpb.28.3057