(2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-tetrahydroacridine

Base Information

• Chemical Name: (2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-tetrahydroacridine
• CAS No.: 1214747-75-7
• Molecular Formula: C₁₆H₁₈N₂
• Molecular Weight: 238.332
• Mol file: 1214747-75-7.mol

Synonyms:(2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-tetrahydroacridine

Chemical Property of (2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-tetrahydroacridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-tetrahydroacridine

There total 1 articles about (2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-tetrahydroacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

(1R,5S)-(+)-nopinone (38651-65-9) + anthranilic acid nitrile (1885-29-6) → (2R,4R)-9-amino-2,4-methano-3,3-dimethyl-1,2,3,4-tetrahydroacridine (1214747-75-7)

Guidance literature:

(1R,5S)-(+)-nopinone; anthranilic acid nitrile; With boron trifluoride diethyl etherate; In toluene; for 24h; Inert atmosphere; Reflux;

With water; sodium hydroxide; for 24h; regioselective reaction; Reflux;

DOI:10.1016/j.ejmech.2009.10.039

upstream raw materials:

(1R,5S)-(+)-nopinone

anthranilic acid nitrile