3-methoxy-6-methyl-2-phenyl-N[(S)-1-phenylpropyl]quinoline-4-cvarboxamide

Base Information

• Chemical Name: 3-methoxy-6-methyl-2-phenyl-N[(S)-1-phenylpropyl]quinoline-4-cvarboxamide
• CAS No.: 1033051-02-3
• Molecular Formula: C₂₇H₂₆N₂O₂
• Molecular Weight: 410.516
• Mol file: 1033051-02-3.mol

Synonyms:3-methoxy-6-methyl-2-phenyl-N[(S)-1-phenylpropyl]quinoline-4-cvarboxamide

Chemical Property of 3-methoxy-6-methyl-2-phenyl-N[(S)-1-phenylpropyl]quinoline-4-cvarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 3-methoxy-6-methyl-2-phenyl-N[(S)-1-phenylpropyl]quinoline-4-cvarboxamide

There total 1 articles about 3-methoxy-6-methyl-2-phenyl-N[(S)-1-phenylpropyl]quinoline-4-cvarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

bis{bis(trimethylsilyl)amido}(methyl)(iodo)tin(IV) (60228-61-7) + 6-Iodo-3-methoxy-2-phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide (765296-48-8) → 3-methoxy-6-methyl-2-phenyl-N[(S)-1-phenylpropyl]quinoline-4-cvarboxamide (1033051-02-3)

Guidance literature:

With tetrabutyl ammonium fluoride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; at 120 ℃; for 0.166667h;

DOI:10.1055/s-2008-1032206

upstream raw materials:

bis{bis(trimethylsilyl)amido}(methyl)(iodo)tin(IV)

6-Iodo-3-methoxy-2-phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide