5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine

Base Information

Chemical Name:5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine
CAS No.:1390625-40-7
Molecular Formula:C₃₇H₄₅N₅O₆Si
Molecular Weight:683.88
Hs Code.:

5'-O-(tert-butyldimethylsilyl)-N<SUP>2</SUP>-(4-methoxytrityl)-2'-C-methylguanosine

Synonyms:5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine

Chemical Property:

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Technology Process of 5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine

There total 3 articles about 5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₇H₂₉N₅O₅Si

: 14470-28-1
mono-4-methoxytrityl chloride

: 1390625-40-7
5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine

Guidance literature:: With pyridine; at 57 ℃; for 20h;
DOI:10.3998/ark.5550190.0013.520

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1390625-40-7
5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 24 h / 20 °C

2: pyridine / 20 h / 57 °C

With pyridine;
DOI:10.3998/ark.5550190.0013.520

Reference yield:

: 374750-30-8
2'-C-methylguanosine

: 1390625-40-7
5'-O-(tert-butyldimethylsilyl)-N²-(4-methoxytrityl)-2'-C-methylguanosine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 24 h / 20 °C

2: pyridine / 20 h / 57 °C

With pyridine;
DOI:10.3998/ark.5550190.0013.520