28-hydroxy-β-amyrone

Base Information

• Chemical Name: 28-hydroxy-β-amyrone
• CAS No.: 18100-50-0
• Molecular Formula: C₃₀H₄₈O₂
• Molecular Weight: 440.71
• Mol file: 18100-50-0.mol

Synonyms:28-hydroxy-β-amyrone

Chemical Property of 28-hydroxy-β-amyrone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 28-hydroxy-β-amyrone

There total 11 articles about 28-hydroxy-β-amyrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3-spiro[1',2']dioxolanerythrodiol → 28-hydroxy-β-amyrone (18100-50-0,6154-89-8)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; at 100 ℃; for 1h;

DOI:10.1021/np100064m

Reference yield: 83.0%

3-oxoolean-12-en-28-al (33608-08-1,35738-60-4) → 28-hydroxy-β-amyrone (18100-50-0,6154-89-8)

Guidance literature:

With sodium tetrahydroborate; acetylacetone; In tetrahydrofuran; at 0 - 20 ℃; for 3.66667h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c9nj03210j

Reference yield:

Oleanolic acid (508-02-1) → 28-hydroxy-β-amyrone (18100-50-0,6154-89-8)

Guidance literature:

Multi-step reaction with 5 steps

1: Jones reagent / dichloromethane; acetone / 0 °C

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C

3: pyridinium p-toluenesulfonate / toluene / 4 h / 110 °C

4: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C

5: hydrogenchloride / tetrahydrofuran; water / 1 h / 100 °C

With hydrogenchloride; lithium aluminium tetrahydride; Jones reagent; pyridinium p-toluenesulfonate; potassium carbonate; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; 1: Jones oxidation;

DOI:10.1021/np100064m

upstream raw materials:

3-oxoolean-12-en-28-al

erythrodiol

Oleanolic acid

Oleanonsaeure

Downstream raw materials:

3-oxo-28-(benzylsuccinyl-4')erythrane

C₄₅H₅₈O₅

C₄₀H₅₆O₅

C₃₈H₅₂O₅

Refernces

• 1、 Sui, Guoqing,Lv, Qingyun,Song, Xiaoqing,Guo, Huihui,Dai, Jiatong,Ren, Li,Lee, Chi-Sing,Zhou, Wenming,Hao, Hong-Dong. "Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone". supporting information. p. 15793 - 15796. Retrieved 2019/10/19.
• 2、 -. "COMPOSITIONS COMPRISING TRITERPENOIDS". Page/Page column 83; 84. . Retrieved 2017/04/11.