C₅₁H₆₃N₃O₃

Base Information

• Chemical Name: C₅₁H₆₃N₃O₃
• CAS No.: 201002-42-8
• Molecular Formula: C₅₁H₆₃N₃O₃
• Molecular Weight: 766.08
• Mol file: 201002-42-8.mol

Synonyms:C₅₁H₆₃N₃O₃

Chemical Property of C₅₁H₆₃N₃O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₁H₆₃N₃O₃

There total 1 articles about C₅₁H₆₃N₃O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C37H51N3O3 (201002-48-4) + benzyl bromide (100-39-0) → C51H63N3O3 (201002-42-8)

Guidance literature:

C₃₇H₅₁N₃O₃; With sodium hydroxide; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 4.5h; Inert atmosphere;

DOI:10.1016/j.tet.2013.06.051

Reference yield:

C51H63N3O3 (201002-42-8) → (2S,3S,4S)-2-azido-3,4-di-O-benzyl-octadecan-1,3,4-triol (202812-10-0)

Guidance literature:

With acetic acid; In water; at 60 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2013.06.051

Reference yield:

C51H63N3O3 (201002-42-8) → (2R,3S,4R)-2-hexacosylamino-3,4-di-O-benzyloctadecanoic acid (1448529-93-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: acetic acid / water / 60 °C / Inert atmosphere

2.1: triphenylphosphine / tetrahydrofuran / 0.5 h / 60 °C / Inert atmosphere

2.2: 4 h / 60 °C

3.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Inert atmosphere

4.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 12 h / Inert atmosphere

4.2: 0.5 h / Inert atmosphere

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/j.tet.2013.06.051

upstream raw materials:

C₃₇H₅₁N₃O₃

benzyl bromide

Downstream raw materials:

(2R,3S,4R)-2-hexacosylamino-3,4-di-O-benzyloctadecanoic acid

3,4 di-O-benzylphytosphingosine

(2S,3S,4S)-2-azido-3,4-di-O-benzyl-octadecan-1,3,4-triol

(2S,3S,4R)-2-hexacosylamino-3,4-di-O-benzyl-1,3,4-octadecanetriol