(E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime

Base Information

• Chemical Name: (E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime
• CAS No.: 1140531-56-1
• Molecular Formula: C₁₆H₂₂N₂O₂
• Molecular Weight: 274.363
• Mol file: 1140531-56-1.mol

Synonyms:(E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime

Chemical Property of (E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime

There total 2 articles about (E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

vinylcaprolactam (2235-00-9,25189-83-7) + p-methylbenzaldehyde oxime (3717-15-5) → (E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime (1140531-56-1)

Guidance literature:

With 2,6-di-tert-butyl-pyridine; tris-(4-bromophenyl)aminium hexachloroantimonate; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2008.01.048

Reference yield: 89.0%

vinylcaprolactam (2235-00-9,25189-83-7) + (Z)-4-methylbenzaldehyde oxime (3717-16-6) → (E)-4-methylbenzaldehyde O-1-(azepan-2-on-1-yl)ethyloxime (1140531-56-1)

Guidance literature:

With 2,6-di-tert-butyl-pyridine; tris(4-bromophenyl)aminium hexachloroantimonate; In dichloromethane; at 20 ℃; for 0.166667h;

DOI:10.1016/j.tet.2009.01.025

upstream raw materials:

vinylcaprolactam

p-methylbenzaldehyde oxime

(Z)-4-methylbenzaldehyde oxime

Refernces

• 1、 Jia, Xiao-dong,Da, Yu-xia,Yang, Cai-xia,Yang, Li,Liu, Zhong-li. "O-Alkylation of oxime with N-vinyl lactams induced by radical cation". . p. 1786 - 1789. Retrieved 2008/09/18.