1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

Base Information

Chemical Name:1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline
CAS No.:1315179-85-1
Molecular Formula:C₂₃H₁₉BrFN₃O₃
Molecular Weight:484.325
Hs Code.:

Synonyms:1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

Suppliers and Price of 1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

There total 3 articles about 1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1315180-28-9
(Z)-3-(5-acetylamino-4-bromo-2-fluorophenylamino)-1-(4-(3, 5-dimethylisoxazol-4-yl)-2-fluorophenyl)-2-buten-1-one

: 1315179-85-1
1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 75 - 80 ℃; for 4.5h;

Reference yield:

: 1315180-19-8
tert-butyl 5-amino-4-bromo-2-fluorophenylcarbamate

: 1315179-85-1
1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / ethyl acetate / 3.25 h / 20 °C

1.2: 7.83 h / 20 °C

2.1: acetic acid / ethanol / 1.5 h / 70 - 80 °C

3.1: potassium carbonate / dimethyl sulfoxide / 4.5 h / 75 - 80 °C

With potassium carbonate; acetic acid; triethylamine; In ethanol; dimethyl sulfoxide; ethyl acetate;

Reference yield:

: 1315180-22-3
N-(5-amino-2-bromo-4-fluorophenyl)acetamide trifluoroacetate

: 1315179-85-1
1-(5-acetylamino-4-bromo-2-fluorophenyl)-7-(3, 5-dimethylisoxazol-4-yl)-2-methyl-1, 4-dihydro-4-oxoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / ethanol / 1.5 h / 70 - 80 °C

2: potassium carbonate / dimethyl sulfoxide / 4.5 h / 75 - 80 °C

With potassium carbonate; acetic acid; In ethanol; dimethyl sulfoxide;