5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

Base Information

Chemical Name:5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone
CAS No.:1310584-41-8
Molecular Formula:C₂₂H₁₃F₂N₃O
Molecular Weight:373.362
Hs Code.:

Synonyms:5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

Suppliers and Price of 5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

There total 5 articles about 5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 56341-41-4
5-fluoroindol-2(3H)-one

: 610278-21-2
3-(2-fluorophenyl)imidazo[1,5-a]pyridine-1-carbaldehyde

: 1310584-41-8
5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

Guidance literature:: With piperidine; In methanol; for 3h; Reflux;
DOI:10.1016/j.ejmech.2011.03.027

Reference yield:

: 293759-48-5
2-fluoro-N-(pyridin-2-ylmethyl)benzamide

: 1310584-41-8
5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

Guidance literature:: Multi-step reaction with 3 steps

1: trichlorophosphate / 3 h / Reflux

2: trichlorophosphate / 2 h / Heating

3: piperidine / methanol / 3 h / Reflux

With piperidine; trichlorophosphate; In methanol;
DOI:10.1016/j.ejmech.2011.03.027

Reference yield:

: 3731-51-9
2-(Aminomethyl)pyridine

: 1310584-41-8
5-fluoro-3-(E)-1-[3-(2-fluorophenyl)imidazo[1,5-a]pyridin-1-yl]methylidene-2-indolinone

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / tetrahydrofuran / 3 h / 0 - 20 °C

2: trichlorophosphate / 3 h / Reflux

3: trichlorophosphate / 2 h / Heating

4: piperidine / methanol / 3 h / Reflux

With piperidine; triethylamine; trichlorophosphate; In tetrahydrofuran; methanol;
DOI:10.1016/j.ejmech.2011.03.027