3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

Base Information

Chemical Name:3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal
CAS No.:947595-21-3
Molecular Formula:C₂₈H₃₆N₂O₅
Molecular Weight:480.604
Hs Code.:

Synonyms:3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

Suppliers and Price of 3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

There total 3 articles about 3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 109224-71-7
2-(aminomethyl)-2-(3,4-dimethoxyphenyl)-1,2-dioxolane

: 141807-59-2
8-methyl-3S-p-tolyl-8-azabicyclo[3.2.1]octane-2S-carboxylic acid

: 947595-21-3
3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

Guidance literature:: With 1-hydroxy-7-aza-benzotriazole; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; at 25 ℃;
DOI:10.1021/jm0703035

Reference yield:

: 187101-52-6
2-azido-1-(3,4-dimethoxyphenyl)ethanone

: 947595-21-3
3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

Guidance literature:: Multi-step reaction with 3 steps

1.1: 80 percent / boron trifluoride etherate / CH₂Cl₂ / 20 °C

2.1: triphenylphosphine / tetrahydrofuran

2.2: 85 percent / water / tetrahydrofuran

3.1: 86 percent / 1-hydroxy-7-azabenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 25 °C

With 1-hydroxy-7-aza-benzotriazole; boron trifluoride diethyl etherate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 2.1: Staudinger reaction;
DOI:10.1021/jm0703035

Reference yield:

: 1835-02-5
2-Bromo-1-(3,4-dimethoxyphenyl)ethanone

: 947595-21-3
3β-(4-methylphenyl)tropane-2β-N-3,4-dimethoxyphenacylcarboxamide ethylene ketal

Guidance literature:: Multi-step reaction with 4 steps

1.1: 87 percent / sodium azide / dimethylsulfoxide / 20 °C

2.1: 80 percent / boron trifluoride etherate / CH₂Cl₂ / 20 °C

3.1: triphenylphosphine / tetrahydrofuran

3.2: 85 percent / water / tetrahydrofuran

4.1: 86 percent / 1-hydroxy-7-azabenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 25 °C

With sodium azide; 1-hydroxy-7-aza-benzotriazole; boron trifluoride diethyl etherate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triphenylphosphine; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; 3.1: Staudinger reaction;
DOI:10.1021/jm0703035