(S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate

Base Information

• Chemical Name: (S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate
• CAS No.: 1296698-69-5
• Molecular Formula: C₂₀H₃₀N₂O₅
• Molecular Weight: 378.469
• Mol file: 1296698-69-5.mol

Synonyms:(S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate

Chemical Property of (S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate

There total 1 articles about (S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

di-tert-butyl-diazodicarboxylate (870-50-8) + (2RS)-2-phenylbutanal (2439-43-2) → (S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate (1296698-69-5)

Guidance literature:

With 9-epi-9-amino-9-deoxyquinine; (R)-10-camphorsulfonic acid; In chloroform; at 20 ℃; for 24h; optical yield given as %ee; enantioselective reaction; sealed vial;

DOI:10.1021/ol200747x

Reference yield: 71.0%

(S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate (1296698-69-5) + acrolein (107-02-8,25068-14-8) → C18H24N2O3 (1431642-22-6)

Guidance literature:

With 9-amino-(9-deoxy)-epi-quinine; trifluoroacetic acid; In chloroform; at 20 ℃; for 16h; enantioselective reaction;

DOI:10.1002/chem.201202024

Reference yield:

(S)-di-tert-butyl 1-(1-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate (1296698-69-5) → C20H30N2O6

Guidance literature:

With sodium chlorite; potassium dihydrogenphosphate; dihydrogen peroxide; In methanol; water; acetonitrile; at 0 - 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2011.06.063

upstream raw materials:

di-tert-butyl-diazodicarboxylate

(2RS)-2-phenylbutanal

Downstream raw materials:

C₂₁H₃₂N₂O₆

(S)-α-ethyl-α-phenylglycine methyl ester

C₁₈H₂₄N₂O₃