<2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile

Base Information

• Chemical Name: <2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile
• CAS No.: 131581-04-9
• Molecular Formula: C₁₃H₁₆N₂
• Molecular Weight: 200.283
• Mol file: 131581-04-9.mol

Synonyms:<2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile

Chemical Property of <2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of <2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile

There total 6 articles about <2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-allyl-2-(2-methylcyclohex-1-en-1-yl)malononitrile → <2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile (131581-04-9)

Guidance literature:

In toluene; at 150 ℃; for 20h;

DOI:10.1002/anie.201608863

Reference yield: 69.0%

2-methyl-2-allylcyclohexanone (16178-87-3) + malononitrile (109-77-3) → <2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile (131581-04-9)

Guidance literature:

With piperidine; acetic acid; 3-amino propanoic acid; In benzene; for 72h; Heating;

DOI:10.1071/CH9901309

Reference yield:

allyl 2-(dicyanomethylene)-1-methylcyclohexane-1-carboxylate → <2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>propanedinitrile (131581-04-9)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 0.03 h / Schlenk technique

2: toluene / 20 h / 150 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; toluene; 2: |Cope Rearrangement;

DOI:10.1002/anie.201608863

upstream raw materials:

2-methyl-2-allylcyclohexanone

malononitrile

cyclohexanone-2-carboxylic acid

allyl 2-oxocyclohexane-1-carboxylate