16178-87-3

Upstream product

• 583-60-8 2-Methylcyclohexanone 
• 1196-73-2 1-acetoxy-2-methylcyclohexene 
• 106-95-6 allyl bromide 
• 32116-69-1 2-n-Butylthiomethylen-cyclohexanon 
• 591-87-7 Allyl acetate 
• 21750-52-7 1-tri-n-butylstannyloxy-2-methylcyclohex-1-ene 
• 35466-83-2 allyl methyl carbonate 
• 86950-89-2 allyl (2-methylcyclohex-1-en-1-yl)carbonate 
• 100747-79-3 N-allyl-N-phenyl-2-methyl-1-cyclohexenylamine 
• 107-18-6 allyl alcohol 
• 2937-50-0 Allyl chloroformate 
• 20007-02-7 cyclohexyl(2-methylcyclohexylidene)amine 
• 107-05-1 3-chloroprop-1-ene 
• 19980-35-9 1-trimethylsilyloxy-2-methyl-1-cyclohexene 

Downstream Products

• 57620-47-0 2-allyl-2-methyl-cyclohexanone oxime 
• 78707-66-1 2-Allyl-1-benzenesulfinylmethyl-2-methyl-cyclohexanol 
• 131581-11-8 (E)-<2'-methyl-2'-(prop-2''-enyl)cyclohexylidene>acetonitrile 
• 105643-70-7 (1-Methyl-2-oxo-cyclohexyl)-acetaldehyde 
• 58711-31-2 (1-methyl-2-oxo-cyclohexyl)-acetic acid 
• 861618-11-3 2-Allyl-2-methyl-cyclohexanol 
• 64-18-6 formic acid 
• 277307-93-4 2-(diethoxy-phosphoryl)-4-ethoxythiocarbonylsulfanyl-5-(1-methyl-2-oxo-cyclohexyl)-pentanoic acid ethyl ester 
• 812639-07-9 (2S)-2-methyl-2-(2-propen-1-yl)cyclohexanone 
• 812639-25-1 (2E)-2-[(2S)-2-methyl-2-(2-propenyl)cyclohexylidene]hydrazinecarboxamide 

Relevant academic research and scientific papers

PALLADIUM-CATALYZED ALLYLATION OF KETONES AND ALDEHYDES VIA ALLYL ENOL CARBONATES

Rearrangement of allyl enol carbonates, prepared from ketones or aldehydes by trapping their enolates with allyl chloroformate, to give α-allyl ketones or aldehydes regioselectively is catalyzed by palladium-phosphine complexes under mild conditions.

ALLYLATION OF KETONES VIA THEIR ENOL ACETATES CATALYZED BY PALLADIUM-PHOSPHINE COMPLEXES AND ORGANOTIN COMPOUNDS

Enol acetates are converted to allyl ketones by the reaction of allylic carbonates in the presence of palladium-phosphine complex and tin alkoxide as bimetallic catalysts.

SYNTHESIS OF γ,δ-UNSATURATED KETONES BY THE INTRAMOLECULAR DECARBOXYLATIVE ALLYLATION OF ALLYL β-KETO CARBOXYLATES AND ALKENYL ALLYL CARBONATES CATALYZED BY MOLYBDENUM, NICKEL, AND RHODIUM COMPLEXES

Allyl β-keto carboxylates and alkenyl allyl carbonates were converted to γ,δ-unsaturated ketones by the intramolecular decarboxylative allylation catalyzed by molybdenum, nickel, and rhodium complexes.

Biocatalytic Conversion of Cyclic Ketones Bearing α-Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium-Sized Carbocycles

Cyclic ketones bearing α-quaternary stereocenters underwent efficient kinetic resolution using cyclohexanone monooxygenase (CHMO) from Acinetobacter calcoaceticus. Lactones possessing tetrasubstituted stereocenters were obtained with high enantioselectivi

Selective Synthesis of Cyclooctanoids by Radical Cyclization of Seven-Membered Lactones: Neutron Diffraction Study of the Stereoselective Deuteration of a Chiral Organosamarium Intermediate

Seven-membered lactones undergo selective SmI2–H2O-promoted radical cyclization to form substituted cyclooctanols. The products arise from an exo-mode of cyclization rather than the usual endo-attack employed in the few radical syntheses of cyclooctanes. The process is terminated by the quenching of a chiral benzylic samarium. A labeling experiment and neutron diffraction study have been used for the first time to probe the configuration and highly diastereoselective deuteration of a chiral organosamarium intermediate.

An Efficient Protocol for the Palladium-Catalyzed Asymmetric Decarboxylative Allylic Alkylation Using Low Palladium Concentrations and a Palladium(II) Precatalyst

Enantioselective catalytic allylic alkylation for the synthesis of 2-alkyl-2-allylcycloalkanones and 3,3-disubstituted pyrrolidinones, piperidinones and piperazinones has been previously reported by our laboratory. The efficient construction of chiral all

Enantioselective, catalytic allylation of ketones and olefins

Compounds containing a substituted or unsubstituted allyl group directly bound to a chiral carbon atom are prepared enantioselectively. Starting reactants are either chiral or achiral, and may or may not contain an attached allyloxycarbonyl group as a sub

Sulfonamide peri-substituted bicyclics for occlusive artery disease

Acyl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:

ARYL SULFONAMIDE PERI-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula (I). A representative example is formula (II

CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE

Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.