16178-87-3Relevant academic research and scientific papers
PALLADIUM-CATALYZED ALLYLATION OF KETONES AND ALDEHYDES VIA ALLYL ENOL CARBONATES
Tsuji, Jiro,Minami, Ichiro,Shimizu, Isao
, p. 1793 - 1796 (1983)
Rearrangement of allyl enol carbonates, prepared from ketones or aldehydes by trapping their enolates with allyl chloroformate, to give α-allyl ketones or aldehydes regioselectively is catalyzed by palladium-phosphine complexes under mild conditions.
ALLYLATION OF KETONES VIA THEIR ENOL ACETATES CATALYZED BY PALLADIUM-PHOSPHINE COMPLEXES AND ORGANOTIN COMPOUNDS
Tsuji, Jiro,Minami, Ichiro,Shimizu, Isao
, p. 4713 - 4714 (1983)
Enol acetates are converted to allyl ketones by the reaction of allylic carbonates in the presence of palladium-phosphine complex and tin alkoxide as bimetallic catalysts.
SYNTHESIS OF γ,δ-UNSATURATED KETONES BY THE INTRAMOLECULAR DECARBOXYLATIVE ALLYLATION OF ALLYL β-KETO CARBOXYLATES AND ALKENYL ALLYL CARBONATES CATALYZED BY MOLYBDENUM, NICKEL, AND RHODIUM COMPLEXES
Tsuji, Jiro,Minami, Ichiro,Shimizu, Isao
, p. 1721 - 1724 (1984)
Allyl β-keto carboxylates and alkenyl allyl carbonates were converted to γ,δ-unsaturated ketones by the intramolecular decarboxylative allylation catalyzed by molybdenum, nickel, and rhodium complexes.
Biocatalytic Conversion of Cyclic Ketones Bearing α-Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium-Sized Carbocycles
Morrill, Charlotte,Jensen, Chantel,Just-Baringo, Xavier,Grogan, Gideon,Turner, Nicholas J.,Procter, David J.
supporting information, p. 3692 - 3696 (2018/03/21)
Cyclic ketones bearing α-quaternary stereocenters underwent efficient kinetic resolution using cyclohexanone monooxygenase (CHMO) from Acinetobacter calcoaceticus. Lactones possessing tetrasubstituted stereocenters were obtained with high enantioselectivi
Selective Synthesis of Cyclooctanoids by Radical Cyclization of Seven-Membered Lactones: Neutron Diffraction Study of the Stereoselective Deuteration of a Chiral Organosamarium Intermediate
Just-Baringo, Xavier,Clark, Jemma,Gutmann, Matthias J.,Procter, David J.
supporting information, p. 12499 - 12502 (2016/10/13)
Seven-membered lactones undergo selective SmI2–H2O-promoted radical cyclization to form substituted cyclooctanols. The products arise from an exo-mode of cyclization rather than the usual endo-attack employed in the few radical syntheses of cyclooctanes. The process is terminated by the quenching of a chiral benzylic samarium. A labeling experiment and neutron diffraction study have been used for the first time to probe the configuration and highly diastereoselective deuteration of a chiral organosamarium intermediate.
An Efficient Protocol for the Palladium-Catalyzed Asymmetric Decarboxylative Allylic Alkylation Using Low Palladium Concentrations and a Palladium(II) Precatalyst
Marziale, Alexander N.,Duquette, Douglas C.,Craig, Robert A.,Kim, Kelly E.,Liniger, Marc,Numajiri, Yoshitaka,Stoltz, Brian M.
supporting information, p. 2238 - 2245 (2015/07/27)
Enantioselective catalytic allylic alkylation for the synthesis of 2-alkyl-2-allylcycloalkanones and 3,3-disubstituted pyrrolidinones, piperidinones and piperazinones has been previously reported by our laboratory. The efficient construction of chiral all
CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE
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Page/Page column 69, (2010/11/08)
Peri-substituted, fused bicyclic ring carboxylic acids useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed.
Enantioselective, catalytic allylation of ketones and olefins
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Page/Page column 13-14, (2008/06/13)
Compounds containing a substituted or unsubstituted allyl group directly bound to a chiral carbon atom are prepared enantioselectively. Starting reactants are either chiral or achiral, and may or may not contain an attached allyloxycarbonyl group as a sub
Sulfonamide peri-substituted bicyclics for occlusive artery disease
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Page/Page column 72, (2008/06/13)
Acyl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula A representative example is:
ARYL SULFONAMIDE PERI-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE
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Page/Page column 91, (2008/06/13)
Aryl sulfonamide, peri-substituted, fused bicyclic ring compounds useful for the treatment or prophylaxis of a prostaglandin-mediated disease or condition are disclosed. The compounds are of the general formula (I). A representative example is formula (II
