3-Hydroxydecanedioic acid

Base Information

Chemical Name:3-Hydroxydecanedioic acid
CAS No.:73141-46-5
Molecular Formula:C₁₀H₁₈O₅
Molecular Weight:218.25
Hs Code.:
UNII:6X0JEZ4U1Y
DSSTox Substance ID:DTXSID80867719
Nikkaji Number:J682.212F
Wikidata:Q27161368
Metabolomics Workbench ID:2012
Mol file:73141-46-5.mol

Synonyms:3-hydroxydecanedioic acid

Suppliers and Price of 3-Hydroxydecanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-HydroxySebacicAcid
10mg
$ 185.00

Total 10 raw suppliers

Chemical Property of 3-Hydroxydecanedioic acid

Chemical Property:

Boiling Point:426.6 °C at 760 mmHg
Flash Point:225.9 °C
Density:1.207 g/cm³
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:218.11542367
Heavy Atom Count:15
Complexity:202

Purity/Quality:

98% ^*data from raw suppliers

3-HydroxySebacicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C(CCCC(=O)O)CCC(CC(=O)O)O
Uses 3-Hydroxysebacic acid is a normal urinary 3-hydroxydicarboxylic acid metabolite and can be elevated in patients with peroxisomal disorders such as Zellweger syndrome.

Technology Process of 3-Hydroxydecanedioic acid

There total 4 articles about 3-Hydroxydecanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 938447-54-2
3-acetoxy-decanedioic acid

: 73141-46-5
3-hydroxysebacic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; for 12h;
DOI:10.1016/j.tetlet.2007.03.053

Reference yield:

: 938447-50-8
dodeca-1,11-dien-4-ol

: 73141-46-5
3-hydroxysebacic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / Et₃N / CH₂Cl₂ / 3 h

2: 69 percent / RuCl₃*xH₂O; NaIO₄ / acetonitrile; ethyl acetate; H₂O / 12 h

3: 80 percent / LiOH / H₂O; tetrahydrofuran / 12 h

With ruthenium trichloride; lithium hydroxide; sodium periodate; triethylamine; In tetrahydrofuran; dichloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1016/j.tetlet.2007.03.053

Reference yield:

: 938447-52-0
acetic acid 1-allyl-non-8-enyl ester

: 73141-46-5
3-hydroxysebacic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / RuCl₃*xH₂O; NaIO₄ / acetonitrile; ethyl acetate; H₂O / 12 h

2: 80 percent / LiOH / H₂O; tetrahydrofuran / 12 h

With ruthenium trichloride; lithium hydroxide; sodium periodate; In tetrahydrofuran; water; ethyl acetate; acetonitrile;
DOI:10.1016/j.tetlet.2007.03.053