N¹-methyl-2,5-diphenyl-Δ²-1,3,4-thiadiazoline-4-carboxamidine

Base Information

• Chemical Name: N¹-methyl-2,5-diphenyl-Δ²-1,3,4-thiadiazoline-4-carboxamidine
• CAS No.: 71535-31-4
• Molecular Formula: C₁₆H₁₆N₄S
• Molecular Weight: 296.396
• Mol file: 71535-31-4.mol

Synonyms:N¹-methyl-2,5-diphenyl-Δ²-1,3,4-thiadiazoline-4-carboxamidine

Chemical Property of N¹-methyl-2,5-diphenyl-Δ²-1,3,4-thiadiazoline-4-carboxamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹-methyl-2,5-diphenyl-Δ²-1,3,4-thiadiazoline-4-carboxamidine

There total 3 articles about N¹-methyl-2,5-diphenyl-Δ²-1,3,4-thiadiazoline-4-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N1-methyl-2,5-diphenyl-Δ2-1,3,4-thiadiazoline-4-carboxamidine hydrochloride → N1-methyl-2,5-diphenyl-Δ2-1,3,4-thiadiazoline-4-carboxamidine (71535-31-4)

Guidance literature:

With sodium hydroxide; In methanol; water; Heating;

DOI:10.1039/P19820001981

Reference yield:

1-chloro-1,4-diphenyl-2,3-diazabutadiene (32252-82-7) → N1-methyl-2,5-diphenyl-Δ2-1,3,4-thiadiazoline-4-carboxamidine (71535-31-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / ethanol / 1 h / Ambient temperature

2: 88 percent / 1percent NaOH / H₂O; methanol / Heating

With sodium hydroxide; In methanol; ethanol; water;

DOI:10.1039/P19820001981

Reference yield:

1-chloro-1,4-diphenyl-2,3-diazabutadiene (32252-82-7) + 1-(methyl)-thiourea (598-52-7) → N1-methyl-2,5-diphenyl-Δ2-1,3,4-thiadiazoline-4-carboxamidine (71535-31-4)

Guidance literature:

Multistep reaction; (i) EtOH, (ii) NaOH;

DOI:10.1039/c39790000149

upstream raw materials:

1-chloro-1,4-diphenyl-2,3-diazabutadiene

1-(methyl)-thiourea

Downstream raw materials:

N-carbamoyl-2,5-diphenyl-Δ²-1,3,4-thiadiazoline