tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

Base Information

Chemical Name:tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate
CAS No.:1446791-43-0
Molecular Formula:C₂₄H₃₅N₇O₃
Molecular Weight:469.587
Hs Code.:

Synonyms:tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

Suppliers and Price of tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

There total 4 articles about tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 372118-01-9
4,6-dichloro-pyridazine-3-carboxylic acid methyl ester

: 1446791-43-0
tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

: 6-((1R,2S)-2-amino-cyclohexylamino)-4-(6-isopropyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide

Guidance literature:: Multi-step reaction with 3 steps

1: acetonitrile / 21 h / 140 °C

2: ammonia / methanol / 18 h / 50 °C

3: 1-methyl-pyrrolidin-2-one / 120 h / 150 °C

With ammonia; In 1-methyl-pyrrolidin-2-one; methanol; acetonitrile;

Reference yield:

: 1446791-41-8
6-chloro-4-(6-isopropylpyridin-2-ylamino)pyridazine-3-carboxamide

: 365996-30-1
tert-butyl ((1S,2R)-2-aminocyclohexyl)carbamate

: 1446791-43-0
tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

: 6-((1R,2S)-2-amino-cyclohexylamino)-4-(6-isopropyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide

Guidance literature:: In 1-methyl-pyrrolidin-2-one; at 150 ℃; for 120h; Overall yield = 33 mg;

Reference yield:

: 1446791-39-4
methyl 6-chloro-4-(6-isopropylpyridin-2-ylamino)pyridazine-3-carboxylate

: 1446791-43-0
tert-butyl (1S,2R)-2-(6-carbamoyl-5-(6-isopropylpyridin-2-ylamino)pyridazin-3-ylamino)cyclohexylcarbamate

: 6-((1R,2S)-2-amino-cyclohexylamino)-4-(6-isopropyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia / methanol / 18 h / 50 °C

2: 1-methyl-pyrrolidin-2-one / 120 h / 150 °C

With ammonia; In 1-methyl-pyrrolidin-2-one; methanol;