(2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid

Base Information

• Chemical Name: (2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid
• CAS No.: 132606-01-0
• Molecular Formula: C₁₅H₂₁NO₄
• Molecular Weight: 279.336
• Mol file: 132606-01-0.mol

Synonyms:(2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid

Chemical Property of (2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid

There total 1 articles about (2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

C22H30N2O5 → (2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid (132606-01-0)

Guidance literature:

C₂₂H₃₀N₂O₅; With lithium hydroxide monohydrate; dihydrogen peroxide; In tetrahydrofuran; water; at 0 ℃; for 0.5h;

With sodium sulfite; In tetrahydrofuran; water; at 0 ℃; for 0.5h;

DOI:10.1016/j.tetasy.2008.12.023

Reference yield: 92.0%

(2R)-([{(benzyloxy)carbonyl}amino]methyl)-4-methylpentanoic acid (132606-01-0) → (2R)-([amino]methyl)-4-methylpentanoic acid (210345-89-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 4h; under 760.051 Torr; enantioselective reaction;

DOI:10.1016/j.tetasy.2008.12.023

Downstream raw materials:

(2R)-([amino]methyl)-4-methylpentanoic acid