N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide

Base Information

• Chemical Name: N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide
• CAS No.: 1243327-74-3
• Molecular Formula: C₂₈H₂₅BrN₂O
• Molecular Weight: 485.423
• Mol file: 1243327-74-3.mol

Synonyms:N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide

Chemical Property of N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide

Chemical Property:

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MSDS Files:

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Technology Process of N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide

There total 1 articles about N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

N,N-dibenzylglycine (17360-47-3) + 2’-bromo-[1,1’-biphenyl]-2-amine (54147-91-0) → N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide (1243327-74-3)

Guidance literature:

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In dichloromethane; at 20 - 27 ℃; for 73h; under 720 - 770 Torr;

DOI:10.1021/jo101137r

Reference yield: 99.0%

N-(2'-bromobiphenyl-2-yl)-2-dibenzylaminoacetamide (1243327-74-3) + methyl iodide (74-88-4) → N2,N2-dibenzyl-N1-(2'-bromobiphenyl-2-yl)-N1-methylglycinamide (1243327-87-8)

Guidance literature:

With sodium hydride; In tetrahydrofuran; mineral oil; at 20 - 27 ℃; for 0.166667h; under 720 - 770 Torr;

DOI:10.1021/jo101137r

upstream raw materials:

N,N-dibenzylglycine

2’-bromo-[1,1’-biphenyl]-2-amine

Downstream raw materials:

N₂,N₂-dibenzyl-N₁-(2'-bromobiphenyl-2-yl)-N₁-methylglycinamide