C₂₉H₃₉ClO₇

Base Information

• Chemical Name: C₂₉H₃₉ClO₇
• CAS No.: 1360568-82-6
• Molecular Formula: C₂₉H₃₉ClO₇
• Molecular Weight: 535.077
• Mol file: 1360568-82-6.mol

Synonyms:C₂₉H₃₉ClO₇

Chemical Property of C₂₉H₃₉ClO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₉H₃₉ClO₇

There total 6 articles about C₂₉H₃₉ClO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanone (461432-22-4) → C29H39ClO7 (1360568-82-6) + (2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-((1-ethylcyclohexyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol (1360568-81-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: aluminum (III) chloride / dichloromethane / 12 h / 20 °C / Inert atmosphere

2.1: triethylsilane; boron trifluoride diethyl etherate / diethyl ether; dichloromethane; acetonitrile / 16 h / 20 °C / Inert atmosphere

3.1: caesium carbonate / N,N-dimethyl-formamide / 120 °C

4.1: tert.-butyl lithium / tetrahydrofuran; toluene / 2 h / -78 °C

4.2: 2 h / -78 °C

With triethylsilane; boron trifluoride diethyl etherate; tert.-butyl lithium; caesium carbonate; aluminum (III) chloride; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

4-bromo-1-chloro-2-(4-((1-ethylcyclohexyl)methoxy)benzyl)benzene (1360568-80-4) + (3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one (32469-28-6,55515-28-1,55515-29-2,32384-65-9) → C29H39ClO7 (1360568-82-6) + (2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-((1-ethylcyclohexyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol (1360568-81-5)

Guidance literature:

4-bromo-1-chloro-2-(4-((1-ethylcyclohexyl)methoxy)benzyl)benzene; (3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one; With tert.-butyl lithium; In tetrahydrofuran; toluene; at -78 ℃; for 2h;

With methanesulfonic acid; In tetrahydrofuran; toluene; at -78 ℃; for 2h;

Reference yield:

5-bromo-2-chlorobenzoic acid (21739-92-4) → C29H39ClO7 (1360568-82-6) + (2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-((1-ethylcyclohexyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol (1360568-81-5)

Guidance literature:

Multi-step reaction with 6 steps

1.1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 12 h / 20 °C

2.1: aluminum (III) chloride / dichloromethane / 1 h / 0 °C

3.1: aluminum (III) chloride / dichloromethane / 12 h / 20 °C / Inert atmosphere

4.1: triethylsilane; boron trifluoride diethyl etherate / diethyl ether; dichloromethane; acetonitrile / 16 h / 20 °C / Inert atmosphere

5.1: caesium carbonate / N,N-dimethyl-formamide / 120 °C

6.1: tert.-butyl lithium / tetrahydrofuran; toluene / 2 h / -78 °C

6.2: 2 h / -78 °C

With triethylsilane; thionyl chloride; boron trifluoride diethyl etherate; tert.-butyl lithium; caesium carbonate; aluminum (III) chloride; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile;

upstream raw materials:

5-bromo-2-chlorobenzoic acid

D-Glucono-1,5-lactone

(5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanone

4-bromo-1-chloro-2-(4-((1-ethylcyclohexyl)methoxy)benzyl)benzene