tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane

Base Information

• Chemical Name: tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane
• CAS No.: 932699-71-3
• Molecular Formula: C₃₃H₄₄O₃Si
• Molecular Weight: 516.796
• Mol file: 932699-71-3.mol

Synonyms:tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane

Chemical Property of tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane

There total 1 articles about tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

4-benzyl-3-(3-hydroxy-2-methyl-oct-7-enoyl)-oxazolidin-2-one (499992-34-6) + p-Anisaldehyde dimethyl acetal (2186-92-7) + tert-butylchlorodiphenylsilane (58479-61-1) → tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane (932699-71-3)

Guidance literature:

Multistep reaction;

DOI:10.1021/ol063087n

Reference yield: 88.0%

tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane (932699-71-3) → 7-(tert-butyl-diphenyl-silanyloxy)-5-(4-methoxy-benzyloxy)-6-methyl-heptanal (932699-72-4)

Guidance literature:

With sodium periodate; osmium(VIII) oxide; water; In 1,4-dioxane; tert-butyl alcohol; at 20 ℃;

DOI:10.1021/ol063087n

Reference yield:

tert-butyl-[3-(4-methoxy-benzyloxy)-2-methyl-oct-7-enyloxy]-diphenyl-silane (932699-71-3) → 5-(tert-butyl-diphenyl-silanyloxy)-4-(tert-butyl-diphenyl-silanyloxymethyl)-1-{7-[2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-1,6-dioxa-spiro[4.5]dec-2-yl}-2-hydroxy-2,4-dimethyl-pentan-1-one

Guidance literature:

Multi-step reaction with 6 steps

1.1: 88 percent / OsO₄; H₂O; NaIO₄ / 2-methyl-propan-2-ol; dioxane / 20 °C

2.1: t-BuLi / diethyl ether / 2 h / -78 - 20 °C

3.1: Dess-Martin periodinane; pyridine / CH₂Cl₂ / 0 - 20 °C

4.1: aq. phosphate buffer; DDQ / CH₂Cl₂ / 0 °C / pH 7

5.1: DMDO

5.2: H₂O / tetrahydrofuran

6.1: TsOH

With pyridine; sodium periodate; osmium(VIII) oxide; phosphate buffer; water; tert.-butyl lithium; Dess-Martin periodane; toluene-4-sulfonic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; diethyl ether; dichloromethane; tert-butyl alcohol; 1.1: Lemieux-Johnson oxidation / 3.1: Dess-Martin oxidation;

DOI:10.1021/ol063087n

upstream raw materials:

4-benzyl-3-(3-hydroxy-2-methyl-oct-7-enoyl)-oxazolidin-2-one

p-Anisaldehyde dimethyl acetal

tert-butylchlorodiphenylsilane

Downstream raw materials:

7-(tert-butyl-diphenyl-silanyloxy)-5-(4-methoxy-benzyloxy)-6-methyl-heptanal