(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

Base Information

Chemical Name:(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate
CAS No.:1104070-00-9
Molecular Formula:C₁₇H₂₃F₂NO₄
Molecular Weight:343.371
Hs Code.:

Synonyms:(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

Suppliers and Price of (S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of (S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

There total 2 articles about (S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.1%

: ethyl (2Z)-3-(4-(1,1-difluoroethyl)phenyl)-2-((((1,1-dimethylethyl)oxy)carbonyl)amino)-2-propenoate

: 1104070-00-9
(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

Guidance literature:: With hydrogen; (+)-1,2-bis-[(2S,5S)-2,5-diethylphospholano]benzene (1,5-cycloctadiene)rhodium(I) trifluoromethanesulfonate; In ethanol; for 16h; under 1551.49 Torr; Sealed tube; Inert atmosphere;

Reference yield: 6.2%

: 913953-73-8
methyl (S)-3-(4-acetylphenyl)-2-((tert-butoxycarbonyl)amino)propanoate

: 1104070-00-9
(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

Guidance literature:: With ethanol; diethylamino-sulfur trifluoride; In dichloromethane; at 90 ℃; for 20h; Sealed tube;

Reference yield: 71.0%

: 1104070-00-9
(S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate

: 1104070-03-2
(S)-tert-butyl 3-(4-(1,1-difluoroethyl)phenyl)-1-hydroxypropan-2-ylcarbamate

Guidance literature:: (S)-methyl 2-(tert-butoxycarbonylamino)-3-(4-(1,1-difluoroethyl)phenyl)propanoate; With lithium borohydride; In tetrahydrofuran; ethanol; at 0 - 20 ℃; for 2h;

With sodium dihydrogenphosphate; water; In tetrahydrofuran; ethanol;