Technology Process of 2-(4-fluorophenyl)-3-phenylquinoline
There total 7 articles about 2-(4-fluorophenyl)-3-phenylquinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis(acetylacetonate)nickel(II); caesium carbonate; triphenylphosphine;
In
1,4-dioxane;
at 90 ℃;
for 4h;
stereoselective reaction;
Inert atmosphere;
DOI:10.1039/c7cc08408k
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium azide; N,N,N,N,N,N-hexamethylphosphoric triamide / 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
2.2: 3 h / -78 °C
3.1: bis(acetylacetonate)nickel(II); triphenylphosphine; caesium carbonate / 1,4-dioxane / 4 h / 90 °C / Inert atmosphere
With
N,N,N,N,N,N-hexamethylphosphoric triamide; bis(acetylacetonate)nickel(II); n-butyllithium; sodium azide; caesium carbonate; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane; hexane;
DOI:10.1039/c7cc08408k
- Guidance literature:
-
Multi-step reaction with 3 steps
1: AlCl3; carbon disulfide
2: ethanolic KOH
With
carbon disulfide; potassium hydroxide; aluminium trichloride;
