5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone

Base Information

Chemical Name:5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone
CAS No.:28757-27-9
Molecular Formula:C21H20 O10
Molecular Weight:432.384
Hs Code.:
Mol file:28757-27-9.mol

Synonyms:Flavone,4',5,7-trihydroxy-, 5-b-D-glucopyranoside (8CI); Apigenin 5-O-glucopyranoside; Apigenin 5-O-b-D-glucopyranoside; Apigenin5-glucoside; Apigenin 5-b-D-glucopyranoside; Salipurpin

Suppliers and Price of 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Apigenin5-O-β-D-Glucopyranoside
5mg
$ 175.00

TRC
Apigenin5-O-β-D-Glucopyranoside
25mg
$ 795.00

Crysdot
Apigenin5-O-beta-D-glucopyranoside 95+%
5mg
$ 640.00

Arctom
Apigenin5-O-beta-D-glucopyranoside
5mg
$ 363.00

Arctom
Apigenin5-O-beta-D-glucopyranoside ≥98%
5mg
$ 248.00

Alichem
Apigenin5-O-beta-D-glucopyranoside
5mg
$ 633.60

Total 18 raw suppliers

Chemical Property of 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone

Chemical Property:

Melting Point:226-227 °C
Boiling Point:814.2±65.0 °C(Predicted)
PKA:6.44±0.40(Predicted)
PSA：170.05000
Density:1.642±0.06 g/cm3(Predicted)
LogP:0.04990
Storage Temp.:2-8°C
Solubility.:Methanol

Purity/Quality:

≥98% ^*data from raw suppliers

Apigenin5-O-β-D-Glucopyranoside ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Apigenin 5-O-β-D-Glucopyranoside is an intermediate in synthesizing Apigenin 5-O-β-D-Glucuronide (A426510), a metabolite of Apigenin (A726500), Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells.

Technology Process of 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone

There total 2 articles about 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133-89-1
UDP-glucose

: 2196-14-7
7,4'-Dihydroxyflavon

: 28757-27-9
Apigenin 5-O-β-D-glucopyranoside

Guidance literature:: With recombinant flavone 5-O-glucosyltransferase; magnesium chloride; In aq. buffer; at 37 ℃; for 0.333333h; pH=7.4; regioselective reaction; Enzymatic reaction;
DOI:10.1038/s41467-017-02168-x

Reference yield:

: 28757-27-9
Apigenin 5-O-β-D-glucopyranoside

Guidance literature:: With sodium hydroxide;

Reference yield:

: 28757-27-9
Apigenin 5-O-β-D-glucopyranoside

: 520-36-5
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Guidance literature:: With malic acid; at 60 ℃; other object of study: half-lives; other reagent : acetic acid, oxalic acid, HCl; other temperature;
DOI:10.1016/0031-9422(91)84200-C