(S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate

Base Information

Chemical Name:(S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate
CAS No.:1207986-88-6
Molecular Formula:C₂₁H₂₉NO₅
Molecular Weight:375.465
Hs Code.:

Synonyms:(S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate

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Technology Process of (S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate

There total 1 articles about (S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 106-96-7
propargyl bromide

: 18938-60-8
(S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate

: 1207986-88-6
(S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide;

Reference yield: 99.0%

: 911196-99-1
5-dimethylamino-naphthalene-1-sulfonic acid-(2-azido-ethyl)amide

: 1207986-88-6
(S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate

: C₃₆H₄₈N₆O₆S

Guidance literature:: With copper(l) iodide; triethylamine; In water; acetonitrile; at 20 ℃; for 16h;
DOI:10.1039/b907741c

Reference yield: 96.0%

: 89896-39-9
ethyl 5-azidovalerate

: 1207986-88-6
(S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-(prop-2-yn-1-yloxy)phenyl)propanoate

: 1207987-02-7
ethyl 5-(4-((4-(3-tert-butoxy-2-(tert-butoxycarbonylamino)-3-oxopropyl)phenoxy)methyl)-1H-1,2,3-triazol-1-yl)pentanoate

Guidance literature:: With bis-triphenylphosphano-copper(I)-butyrate; In dichloromethane; at 28 ℃; for 8h; regioselective reaction;
DOI:10.1039/b920790m