5-azido-pentanoic acid ethyl ester

Base Information

• Chemical Name: 5-azido-pentanoic acid ethyl ester
• CAS No.: 89896-39-9
• Molecular Formula: C7H13N3O2
• Molecular Weight: 171.199
• Mol file: 89896-39-9.mol

Synonyms:5-azidovaleric acid ethyl ester;ethyl 5-azidopentanoate;ethyl-δ-azido valerate;5-Azido-valeriansaeure-aethylester;5-azido-pentanoic acid ethyl ester;

Chemical Property of 5-azido-pentanoic acid ethyl ester

Chemical Property:

• PSA: 76.05000
• LogP: 1.48286

Purity/Quality:

98% ^*data from raw suppliers

5-Azidopentanoicacidethylester 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-azido-pentanoic acid ethyl ester

There total 4 articles about 5-azido-pentanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethyl 5-bromovalerate (14660-52-7) → ethyl 5-azidovalerate (89896-39-9)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2007.05.079

Reference yield:

5-bromopentanoic acid (2067-33-6) → ethyl 5-azidovalerate (89896-39-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / Reflux

2: sodium azide; sodium iodide / N,N-dimethyl-formamide; water / 90 °C

With sodium azide; sulfuric acid; sodium iodide; In water; N,N-dimethyl-formamide;

DOI:10.1002/cjoc.201300703

Reference yield:

ethanol (64-17-5) + 5-bromopentanoic acid (2067-33-6) → ethyl 5-azidovalerate (89896-39-9)

Guidance literature:

Multistep reaction; (i) H₂SO₄, (ii) NaN₃;

DOI:10.1039/jr9620000622

upstream raw materials:

ethanol

5-bromopentanoic acid

ethyl 5-bromovalerate

Downstream raw materials:

piperidin-2-one

5-azidovaleric acid

ethyl 5-(4-((4-(3-tert-butoxy-2-(tert-butoxycarbonylamino)-3-oxopropyl)phenoxy)methyl)-1H-1,2,3-triazol-1-yl)pentanoate

ethyl 5-(4-phenyl-1H-1,2,3-triazol-1-yl)pentanoate