(R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

Base Information

Chemical Name:(R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide
CAS No.:1350639-79-0
Molecular Formula:BrH*C₂₀H₁₈N₄O
Molecular Weight:411.301
Hs Code.:

Synonyms:(R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

Suppliers and Price of (R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

There total 5 articles about (R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: (R)-6-(4-methoxyphenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

: 1350639-79-0
(R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

Guidance literature:: (R)-6-(4-methoxyphenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 24h; Inert atmosphere;

With water; In dichloromethane;
DOI:10.1016/j.ejmech.2011.10.012

Reference yield:

: 173458-92-9
2-amino-3-carboxethyl-5-(4-methoxyphenyl)-pyrrole

: 1350639-79-0
(R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

Guidance literature:: Multi-step reaction with 4 steps

1.1: formic acid / N,N-dimethyl-formamide / 20 h / 150 °C

2.1: trichlorophosphate / 3 h / 90 °C

2.2: pH 12

3.1: butan-1-ol / 24 h / 145 °C / Inert atmosphere

4.1: boron tribromide / dichloromethane / 24 h / 0 - 20 °C / Inert atmosphere

With formic acid; boron tribromide; trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide; butan-1-ol;
DOI:10.1016/j.ejmech.2011.10.012

Reference yield:

: 173458-97-4
4-hydroxy-6-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidine

: 1350639-79-0
(R)-4-(4-((1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1.1: trichlorophosphate / 3 h / 90 °C

1.2: pH 12

2.1: butan-1-ol / 24 h / 145 °C / Inert atmosphere

3.1: boron tribromide / dichloromethane / 24 h / 0 - 20 °C / Inert atmosphere

With boron tribromide; trichlorophosphate; In dichloromethane; butan-1-ol;
DOI:10.1016/j.ejmech.2011.10.012