2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

Base Information

Chemical Name:2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide
CAS No.:1433198-43-6
Molecular Formula:C₂₅H₂₆FN₃O₃
Molecular Weight:435.498
Hs Code.:

Synonyms:2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

Suppliers and Price of 2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

There total 3 articles about 2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: 1433198-39-0
2-(4-(4-fluorophenoxy)phenyl)-6-methylisonicotinic acid

: 1433198-43-6
2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

Guidance literature:: 2-(4-(4-fluorophenoxy)phenyl)-6-methylisonicotinic acid; With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; at 20 ℃; for 0.333333h;

4-(2-AMINOETHYL)MORPHOLINE; In dichloromethane; at 20 ℃; for 20h;

Reference yield:

: 1355052-34-4
2-(4-(4-fluorophenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1433198-43-6
2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium carbonate; bis-triphenylphosphine-palladium(II) chloride / water; 1,2-dimethoxyethane; ethanol / 16 h / 80 °C

1.2: 18 h / 20 °C

2.1: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 0.33 h / 20 °C

2.2: 20 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In 1,2-dimethoxyethane; ethanol; dichloromethane; water;

Reference yield:

: 3998-90-1
2-chloro-6-methyl-isonicotinic acid methyl ester

: 1433198-43-6
2-(4-(4-fluorophenoxy)phenyl)-6-methyl-N-(2-morpholinoethyl)isonicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium carbonate; bis-triphenylphosphine-palladium(II) chloride / water; 1,2-dimethoxyethane; ethanol / 16 h / 80 °C

1.2: 18 h / 20 °C

2.1: benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 0.33 h / 20 °C

2.2: 20 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In 1,2-dimethoxyethane; ethanol; dichloromethane; water;