N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide

Base Information

Chemical Name:N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide
CAS No.:1065586-67-5
Molecular Formula:C₂₅H₂₆F₂N₈O
Molecular Weight:492.531
Hs Code.:

Synonyms:N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide

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Chemical Property of N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide

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Technology Process of N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide

There total 1 articles about N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1065586-62-0
4-chloro-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

: 613-94-5
benzoic acid hydrazide

: 1065586-67-5
N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide

Guidance literature:: In 1-methyl-pyrrolidin-2-one; at 150 ℃; for 3h;

Reference yield:

: 1065586-67-5
N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide

: 1065586-12-0
7-(2-(4-(2,4-Difluorophenyl)piperazin-1-yl)ethyl)-2-phenyl-7H-pyrrolo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine

Guidance literature:: N'-(2-amino-7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzohydrazide; With N,O-bis-(trimethylsilyl)-acetamide; In 1,1,1,3,3,3-hexamethyl-disilazane; at 120 ℃; for 16h;

With hydrogenchloride; In dichloromethane; water; at 20 ℃; for 1h;

With sodium hydroxide; In dichloromethane; water; pH=12;