(Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

Base Information

Chemical Name:(Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester
CAS No.:214683-79-1
Molecular Formula:C₃₄H₆₀O₂Si
Molecular Weight:528.935
Hs Code.:

Synonyms:(Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

Suppliers and Price of (Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

There total 1 articles about (Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 638-45-9
1-Iodohexane

: (Z)-3-(Dimethyl-phenyl-silanyl)-hexadec-4-enoic acid tert-butyl ester

: 214683-79-1
(Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; Yield given; 1.) -78 deg C, 30 min, 2.) -78 deg C, 1 h;
DOI:10.1039/a804275f

Reference yield: 29.0%

: 214683-79-1
(Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

: 214683-72-4
(Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-en-1-ol

Guidance literature:: With 9-borabicyclo[3.3.1]nonane dimer; for 3h; Heating;
DOI:10.1039/a804275f

Reference yield:

: 214683-79-1
(Z)-(2R,3S)-3-(Dimethyl-phenyl-silanyl)-2-hexyl-hexadec-4-enoic acid tert-butyl ester

: 104872-04-0,104872-27-7,104872-28-8,111466-61-6,111466-62-7,111466-63-8,130193-40-7,130193-41-8,130193-42-9,130193-43-0,96829-58-2,1225451-00-2
Orlistat

Guidance literature:: Multi-step reaction with 13 steps

1: 29 percent / 9-BBN / 3 h / Heating

2: imidazole / dimethylformamide / 1 h / Ambient temperature

3: 1.) 9-BBN, 2.) NaOH, H₂O₂ / 1.) reflux, 24 h

4: 91 percent / TfOH / cyclohexane; CH₂Cl₂ / 0.5 h / Ambient temperature

5: 98 percent / TBAF / tetrahydrofuran / 1 h / Ambient temperature

6: 88 percent / PDC / dimethylformamide / 2 h / Ambient temperature

7: 62 percent / Jones' reagent / acetone / 0.75 h / 0 °C

8: 38 percent / Hg(OAc)2, AcOOH, AcOH / 3 h / Ambient temperature

9: benzenesulfonyl chloride, pyridine / 15 h / 0 °C

10: 92 percent / H₂ / 10percent Pd/C / tetrahydrofuran / 15 h

11: DCC, DMAP / CH₂Cl₂; dimethylformamide / 1 h / Ambient temperature

12: H₂ / 10percent Pd/C / tetrahydrofuran / 4 h / Ambient temperature

13: CH₂Cl₂ / 0.25 h / Ambient temperature

With pyridine; 1H-imidazole; peracetic acid; dmap; sodium hydroxide; dipyridinium dichromate; 9-borabicyclo[3.3.1]nonane dimer; jones' reagent; trifluorormethanesulfonic acid; mercury(II) diacetate; tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; acetic acid; benzenesulfonyl chloride; dicyclohexyl-carbodiimide; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; cyclohexane; N,N-dimethyl-formamide; acetone;
DOI:10.1039/a804275f