lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

Base Information

Chemical Name:lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate
CAS No.:1402054-53-8
Molecular Formula:C₂₅H₃₂N₉O₅*Li
Molecular Weight:545.527
Hs Code.:

Synonyms:lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

Suppliers and Price of lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

There total 7 articles about lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1402054-51-6
(S)-5-(5-arnino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidm-2-yl)dihydrofuran-2(3H)-one

: 1402054-53-8
lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

Guidance literature:: With lithium hydroxide monohydrate; water; In tetrahydrofuran; methanol; at 50 ℃; for 1.75h;

Reference yield:

: 929884-34-4
4-hydrazinyl-1-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

: 1402054-53-8
lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; 4-methyl-morpholine / N,N-dimethyl-formamide / 14 h / 20 °C

2: (Z)-trimethylsilyl N-trimethylsilylacetimidate / 20 h / 110 °C / Inert atmosphere

3: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 1.75 h / 50 °C

With 4-methyl-morpholine; lithium hydroxide monohydrate; (Z)-trimethylsilyl N-trimethylsilylacetimidate; water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

Reference yield:

: 929884-17-3
4-chloro-1-(2-chloroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine

: 1402054-53-8
lithium (S)-4-(5-amino-7-(2-(4-(4-(2-methoxyethoxy)phenyl)piperazin-1-yl)ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-4-hydroxybutanoate

Guidance literature:: Multi-step reaction with 6 steps

1: N,N-dimethyl-formamide / 48 h / 20 - 80 °C

2: potassium iodide; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 h / 100 °C

3: hydrogenchloride / dichloromethane; 1,4-dioxane; methanol / 5.5 h / 20 °C

4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; 4-methyl-morpholine / N,N-dimethyl-formamide / 14 h / 20 °C

5: (Z)-trimethylsilyl N-trimethylsilylacetimidate / 20 h / 110 °C / Inert atmosphere

6: water; lithium hydroxide monohydrate / tetrahydrofuran; methanol / 1.75 h / 50 °C

With 4-methyl-morpholine; hydrogenchloride; lithium hydroxide monohydrate; (Z)-trimethylsilyl N-trimethylsilylacetimidate; water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; potassium iodide; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;